Synbiotic Nutritious Drink: Potential and Safety Evaluation


Shaikhin S. Sarmurzina Z. Abitayeva G. Bissenova G. Mussabayeva B. Naimanov Y. Shulgau Z. Khalymbetova A. Abilkhadirov A. Almagambetov K. Temirkhanov A. Bekshin Z.
2024United Scientific Group

Journal of Food Chemistry and Nanotechnology
2024#10Issue 268 - 78 pp.

The increasing concern for health and quality of life has motivated individuals to consume healthier food. Enriching food products with health-promoting additives represents a novel approach within the food industry of Kazakhstan, particularly pertinent due to the adverse environmental and radiation conditions in the Republic. The aim of this study was to develop a new synbiotic nutritional dairy drink (SN) fortified with vitamins, the prebiotic inulin, and the radioactive element blocker potassium iodide and evaluate its physicochemical and sensory properties, shelf life, and safety. In this study, original local strains of Lactobacillus, isolated from traditional Kazakh products, were utilized for the first time. The SN drink was obtained by fermenting natural cows milk with probiotics: Lactobacillus casei 1A, Lactobacillus paracasei 2A, and Lactobacillus brevis 4 LB in the presence of the prebiotic inulin, vitamins A, B1, B2, C and the essential mineral potassium iodide. Titratable acidity (TA) was estimated according to the published technical specification. The viable number of lactobacilli was assessed by plate counting. Sensory evaluation was conducted using a 9-point hedonic scale. The overall viability of probiotic microorganisms of SN drink is maintained for 28 days within the permissible range for beverages according to scientific data. According to sensory analysis, the shelf life of SN drink is determined to be 14 days. The SN drink did not alter the behavior and general conditions of laboratory mice and did not reveal any signs of allergy on the skin and conjunctiva of guinea pigs and rabbits, respectively. The results of the study indicate that the SN drink is safe and suitable for human consumption.

Drink , In vivo , Potassium iodide , Probiotics , Safety , Shelf life , Synbiotics , Vitamins

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Laboratory of Genetics and Biochemistry of Microorganisms, Republican Collection of Microorganisms of the Committee of Science of the Ministry of Education and Science of the Republic of Kazakhstan, Astana, Kazakhstan
Laboratory of Biotechnology, Republican Collection of Microorganisms of the Committee of Science of the Ministry of Education and Science of the Republic of Kazakhstan, Astana, Kazakhstan
Laboratory of Microbiology, Republican Collection of Microorganisms, Kazakhstan
JSC “Astana-Onim” Akmola region, Kazakhstan
National Laboratory Astana, Nazarbayev University, Astana, Kazakhstan
Biobank of Industrial Microorganisms in Republic Collection of Microorganisms of the Ministry of Healthcare of the Republic of Kazakhstan, Astana, Kazakhstan

Laboratory of Genetics and Biochemistry of Microorganisms
Laboratory of Biotechnology
Laboratory of Microbiology
JSC “Astana-Onim” Akmola region
National Laboratory Astana
Biobank of Industrial Microorganisms in Republic Collection of Microorganisms of the Ministry of Healthcare of the Republic of Kazakhstan

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