Sustainable detergent-disinfectant agent based on whey mineralizate and silver nanoparticles for cleaner production in dairy industry


Blinov A. Blinova A. Nagdalian A. Siddiqui S.A. Gvozdenko A. Golik A. Rekhman Z. Filippov D. Shariati M.A. AL-Farga A. Al-maaqar S.M.
December 2024Nature Research

Scientific Reports
2024#14Issue 1

Detergents and disinfectants for dairy industry must meet a variety of characteristics, including low toxicity, high antibacterial activity, and excellent rinsing of pollutants from working surfaces. This work presents an innovative detergent-disinfectant agent based on whey mineralizate and silver nanoparticles (Ag NPs), which allows reducing production costs and ensuring high cleanliness of treated surfaces compared to analogues. For this purpose, a method for obtaining sols of Ag NPs stabilized with didecyldimethylammonium bromide (Ag NPs-DDAB) was developed and optimized using neural network algorithms. Characterization of Ag NPs-DDAB showed particles with a radius of 4.5 nm and 20 nm, stable in the pH range from 2 to 11. An acute toxicity study of Ag NPs in mice showed LD50 = 4230 μg/kg. Based on the degree of accumulation and inhalation toxicity, Ag NPs-DDAB are classified as low-hazard chemicals. The developed detergent-disinfectant had a washability of about 90%, high antimicrobial activity (0.005 mg/mL) against Penicillium roqueforti and a sanitary and hygienic effect on coliforms, general contamination and pathogenic microorganisms, a low-corrosive effect and low toxicity (315 mg/mL) to Danio rerio. It was concluded that the use of detergent-disinfectant agent will completely eliminate the consumption of water for the equipment cleaning process and can be used to clean an electrodialysis unit’s circuits, enabling the utilization of secondary waste from membrane milk processing and promoting resource efficiency and cleaner production in the dairy industry.

Cleaner production , Colloidal silver , Milk , Mineralization , Toxicity , Whey

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Department of Physics and Technology of Nanostructures and Materials, North Caucasus Federal University, Stavropol, 355000, Russian Federation
Laboratory of Food and Industrial Biotechnology, North Caucasus Federal University, Stavropol, 355000, Russian Federation
Independent researcher, Straubing, Germany
Kazakh Research Institute of Processing and Food Industry, Semey Branch of the Institute, 238«G» Gagarin Ave., Almaty, 050060, Kazakhstan
Department of Biochemistry, College of Science, University of Jeddah, Jeddah, 23218, Saudi Arabia
Department of Biology, Faculty of Education, Albaydha University, Al-Baydha, Yemen

Department of Physics and Technology of Nanostructures and Materials
Laboratory of Food and Industrial Biotechnology
Independent researcher
Kazakh Research Institute of Processing and Food Industry
Department of Biochemistry
Department of Biology

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