Synthesis, Characterization and Potential Antimicrobial Activity of Selenium Nanoparticles Stabilized with Cetyltrimethylammonium Chloride


Blinova A. Blinov A. Kravtsov A. Nagdalian A. Rekhman Z. Gvozdenko A. Kolodkin M. Filippov D. Askerova A. Golik A. Serov A. Shariati M.A. Alharbi N.S. Kadaikunnan S. Thiruvengadam M.
December 2023Multidisciplinary Digital Publishing Institute (MDPI)

Nanomaterials
2023#13Issue 24

Selenium nanoparticles (Se NPs) have a number of unique properties that determine the use of the resulting nanomaterials in various fields. The focus of this paper is the stabilization of Se NPs with cetyltrimethylammonium chloride (CTAC). Se NPs were obtained by chemical reduction in an aqueous medium. The influence of the concentration of precursors and synthesis conditions on the size of Se NPs and the process of micelle formation was established. Transmission electron microscopy was used to study the morphology of Se NPs. The influence of the pH of the medium and the concentration of ions in the sol on the stability of Se micelles was studied. According to the results of this study, the concentration of positively charged ions has a greater effect on the particle size in the positive Se NPs sol than in the negative Se NPs sol. The potential antibacterial and fungicidal properties of the samples were studied on Escherichia coli, Micrococcus luteus and Mucor. Concentrations of Se NPs stabilized with CTAC with potential bactericidal and fungicidal effects were discovered. Considering the revealed potential antimicrobial activity, the synthesized Se NPs-CTAC molecular complex can be further studied and applied in the development of veterinary drugs, pharmaceuticals, and cosmetics.

antibacterial properties , CTAC , fungicidal properties , selenium nanoparticles , stability , transmission electron microscopy , ζ-potential

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Physical and Technical Faculty, North-Caucasus Federal University, Stavropol, 355017, Russian Federation
Laboratory of Food and Industrial Biotechnology, North-Caucasus Federal University, Stavropol, 355017, Russian Federation
Chemical and Pharmaceutical Faculty, North-Caucasus Federal University, Stavropol, 355017, Russian Federation
Scientific Department, Semey Branch of the Kazakh Research Institute of Processing and Food Industry, Gagarin Avenue 238G, Almaty, 050060, Kazakhstan
Department of Botany and Microbiology, College of Science, King Saud University, P. O. Box 2455, Riyadh, 11451, Saudi Arabia
Department of Applied Bioscience, Konkuk University, Seoul, 05029, South Korea

Physical and Technical Faculty
Laboratory of Food and Industrial Biotechnology
Chemical and Pharmaceutical Faculty
Scientific Department
Department of Botany and Microbiology
Department of Applied Bioscience

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