Plant Based Polyphenol Associations with Protein: A Prospective Review


Tazeddinova D. Rahman M.R. Hamdan S.B. Matin M.M. Bakri M.K.B. Rahman M.M.
2022North Carolina State University

BioResources
2022#17Issue 41 - 25 pp.

This review discusses the classes of plant polyphenols along with their binding mechanisms with protein molecules. Generally, polyphenols bind in covalent and non-covalent orientations with protein molecules. Their addition to the protein usually results in undesirable flavors and tastes inside the proteins. They also affect the color of the food. Plant polyphenols are found to act in a protective way against cardiovascular disease, neurodegenerative diseases, diabetes, and cancer. In addition to redox activity, their modes of action include the inhibition of key enzymes, modulation of transcription factors or cell receptors, and finally, perturbation of protein aggregates. Dietary polyphenols usually play a key role in protein digestion by forming covalent and non-covalent bonds with proteins. In addition, polyphenols and plant phenolics possess the scavenging ability of reactive oxygen species (ROS), including radical/non-radical oxygen species including HOC•, H2O2, HOCl,1O2 (singlet oxygen), and oxidatively generated radicals derived from LDL biomolecules such as ROOC• and oligonucleic acids.

Digest-ability , Functional properties , Interaction , Millard reaction , Polyphenol-Protein , Reactive oxygen

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Department of Technology and Catering Organization, South Ural State University, Chelyabinsk, Russian Federation
Zhangir Khan Agrarian Technical University, Uralsk, Kazakhstan
Faculty of Engineering, Universiti Malaysia Sarawak, Jalan Datuk Mohammad Musa, Sarawak, Kota Samarahan, Malaysia
Bioorganic and Medicinal Chemistry Laboratory, Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong, Bangladesh
Composite Materials and Engineering Centre, Department of Civil and Environmental Engineering, Washington State University, Pullman, WA, United States
Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah, 21589, Saudi Arabia

Department of Technology and Catering Organization
Zhangir Khan Agrarian Technical University
Faculty of Engineering
Bioorganic and Medicinal Chemistry Laboratory
Composite Materials and Engineering Centre
Department of Chemistry

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