Impact of factors on the growth and activity of lactic acid bacteria for controlling pathogenic microorganisms in kazakhstan
Myktybayeva R. Kozahmetova Z. Sansyzbay A. Boranbayeva T. Mussoyev A. Otebayev Z. Dutbayev Y.
31 December 2024Unique Scientific Publishers
International Journal of Agriculture and Biosciences
2024#13Issue 4617 - 625 pp.
The study aimed to evaluate the influence of various factors on the growth and activity of lactic acid bacteria isolated from shubat and kumis to determine their potential in controlling pathogenic microorganisms in Kazakhstan. Microbiological studies were conducted at the Laboratory of Microbiocenosis and Probiotic Design of the Department of Biological Safety at the Kazakh National Agrarian Research University, and molecular and biological studies were performed at the Institute of Microbiology and Virology. The objective of the study was to evaluate the antimicrobial activity of lactic acid bacteria strains and assess their tolerance to various factors, such as nutrient medium (meat peptone and milk), bile salt concentration (20 and 40%), and sodium chloride concentration (2, 4 and 6%), and the effect of temperature and air on the number of bacteria. R software version 4.3.3 was used for statistical data processing. The variation analysis (ANOVA) was performed using the Kruskall-Wallis test, establishing statistical significance at P<0.05. The results showed the unique activity of each lactic acid bacteria strain against various bacteria and moderate and strong positive correlations between strains and their activity. The importance of optimizing the conditions for the cultivation of lactic acid bacteria was confirmed by the results of the study where various nutrient substrates, temperature, bile, and time had a significant impact on the growth and behavior of bacteria. The results can be used to optimize the production of lactic acid products and the development of new probiotic preparations and to control pathogens in the food industry and veterinary medicine in Kazakhstan.
Correlations , Influence of abiotic factors , Pathogen control , Probiotics , Strain
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Kazakh National Agrarian University, Almaty, Kazakhstan
Kazakh National Agrarian Research University, Almaty, Kazakhstan
Kazakh Scientific Research Veterinary Institute, Almaty, Kazakhstan
Kazakh National Agrarian University
Kazakh National Agrarian Research University
Kazakh Scientific Research Veterinary Institute
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