Comparative Phytochemical, Colloidal, and Antioxidant Profiling of Artemisia albida, Artemisia leucodes, and Artemisia scopaeformis: Potentials for Cosmeceutical and Nutraceutical Applications
Jenis J. Minkayeva A. Yessimova O. Kumargaliyeva S. Shah A.B. Karunakaran T. Gulnur K. Aisa H.A. Baiseitova A.
November 2025Multidisciplinary Digital Publishing Institute (MDPI)
Molecules
2025#30Issue 21
Artemisia albida, Artemisia leucodes, and Artemisia scopaeformis were selected for this study based on their traditional medicinal uses and phytochemical profiles. A. albida exhibited the highest level of extractive substances (20.76%) and showed the greatest concentration of water-soluble polysaccharides (2.14%). Tannins, well known for their astringency and antioxidant activity, were most abundant in A. scopaeformis (2.81%) and A. albida (1.52%). The phenolics coumarins were concentrated in A. scopaeformis (6.49%) and A. leucodes (4.46%). Among the extracts, A. leucodes exhibited the strongest antioxidant activity (DPPH IC50 = 13.53 μM, FRAP = 52.02 μmol TE/g), the highest SPF (23.24), and the most effective DNA protection (91.4%). It indicated a high level of biological effectiveness, with an SPF comparable to natural UV-protection agents and DNA protection exceeding 90%, suggesting potential. Molecular docking confirmed binding of catechin and epicatechin to glutathione peroxidase. Colloidal analysis revealed that hydrolates obtained from A. albida and A. leucodes have significant surface activity, reducing water surface tension to 40–50 mJ/m2, whereas the hydrolate from A. scopaeformis had only a minor effect. Thus, A. leucodes is a strong candidate for multifunctional antioxidant, UV-protective, and skin-regenerating applications.
antioxidants , Artemisia species , DNA oxidation protection , hydrolates , sun protection factor
Text of the article Перейти на текст статьи
Xinjiang Technical Institutes of Physics and Chemistry, Central Asian of Drug Discovery and Development, Chinese Academy of Sciences, Urumqi, 830011, China
University of Chinese Academy of Sciences, Beijing, 100039, China
Research Center for Medicinal Plants, Al-Farabi Kazakh National University, Almaty, 050040, Kazakhstan
Department of Analytical, Colloid Chemistry and Technology of Rare Elements, Faculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, Almaty, 050040, Kazakhstan
Research Institute for Natural Products & Technology, Almaty, 050040, Kazakhstan
College of Pharmacy, Korea University, 30019, Sejong, South Korea
Interdisciplinary Major Program in Innovative Pharmaceutical Sciences, Korea University, Sejong, 30019, South Korea
Centre for Drug Research, Universiti Sains Malaysia, Penang, 11800, Malaysia
Department of Microbiology, Virology and Immunology, Kazakh National Agrarian Research University, Almaty, 050040, Kazakhstan
Division of Applied Life Science, Gyeongsang National University, Jinju, 52828, South Korea
Xinjiang Technical Institutes of Physics and Chemistry
University of Chinese Academy of Sciences
Research Center for Medicinal Plants
Department of Analytical
Research Institute for Natural Products & Technology
College of Pharmacy
Interdisciplinary Major Program in Innovative Pharmaceutical Sciences
Centre for Drug Research
Department of Microbiology
Division of Applied Life Science
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026