Herbal Medicine for the Management of Laxative Activity
Akram M. Thiruvengadam M. Zainab R. Daniyal M. Bankole M.M. Rebezov M. Shariati M.A. Okuskhanova E.
August 2022Bentham Science Publishers
Current Pharmaceutical Biotechnology
2022#23Issue 101269 - 1283 pp.
Constipation is one of the most common and prevalent chronic gastrointestinal conditions across the globe that is treated or managed through various methods. Laxatives are used for the treatment or management of chronic/acute constipation. But due to the adverse effects associated with these laxatives, herbal foods should be considered as alternative therapies for constipation. In this review, the laxative potential of plant-based medicines used for constipation is discussed. Constipation may be caused by various factors such as lifestyle, particular food habits, pregnancy and even due to some medication. Chronic constipation is responsible for different health issues. Pharmacological and non-pharmacological paradigms are applied for the treatment or management of constipation. In the pharmacological way of treatment, medicinal plants have a key role because of their fibrous nature. Numerous plants such as Prunus persica (Rosaceae), Cyamopsis tetragonolobus (Leguminosae), Citrus sinensis (Rutaceae), Planta goovata (Plantaginaceae), Rheum emodi (Polygonaceae), Cassia auriculata (Caesalpinacea), Ricinus communis (Euphorbiaceae), Croton tiglium (Euphorbiaceae), Aloe barbadensis (Liliaceae), Mareya micrantha (Euphorbiaceae), Euphorbia thymifolia (Euphorbiaceae), Cascara sagrada (Rhamnaceae), Cassia angustifolia (Fabaceae) have laxative activity. Medicinal plants possess a significant laxative potential and support their folklore; therefore, further, well-designed clinical-based studies are required to prove and improve the efficacy of herbal medicine for constipation. The present review showed that herbs laxative effect in various in vivo/ in vitro models.
constipation , herbal medicines , Laxative , medicinal effects , non-pharmacological , pharmacological
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Department of Eastern Medicine, Government College University Faisalabad, Pakistan
Department of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul, 05029, South Korea
Faculty of Eastern Medicine, Hamdard University, Karachi, Pakistan
African Centre of Excellence (World Bank) Public Health and Toxicological Research (ACE-PUTOR), University of Port Harcourt, Rivers State, Nigeria
V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences, Moscow, Russian Federation
Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow, Russian Federation
K.G. Razumovsky Moscow State University of Technologies and Management (The First Cossack University), Moscow, 109004, Russian Federation
Shakarim State University of Semey, Semey, Kazakhstan
Department of Eastern Medicine
Department of Crop Science
Faculty of Eastern Medicine
African Centre of Excellence (World Bank) Public Health and Toxicological Research (ACE-PUTOR)
V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences
Prokhorov General Physics Institute of the Russian Academy of Sciences
K.G. Razumovsky Moscow State University of Technologies and Management (The First Cossack University)
Shakarim State University of Semey
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