Molecular targets for the management of cancer using Curcuma longa Linn. phytoconstituents: A Review
Sultana S. Munir N. Mahmood Z. Riaz M. Akram M. Rebezov M. Kuderinova N. Moldabayeva Z. Shariati M.A. Rauf A. Rengasamy K.R.R.
March 2021Elsevier Masson s.r.l.
Biomedicine and Pharmacotherapy
2021#135
Medicinal plants are being used for therapeutic purposes since the dawn of human civilization. The therapeutic efficacy of medicinal plants is due to the presence of wide range phytochemical constituents or secondary metabolites. The medicinal plants are traditionally used for several types of ailments. Even in those pathological conditions where other methods of treatment fail to work. Curcuma longa Linn is very common ingredient used as spice in foods as preservative and coloring material in different part of the world. It has been used as a home remedy for a variety of diseases. Curcuma longa and its isolated constituent curcumin are widely evaluated for anticancer activity. Curcumin possesses broad remedial potential due to its multi-targeting effect against many different carcinoma including leukemia, genitourinary cancers, gastrointestinal cancers and breast cancer etc. Hence, Curcumin has potential for the development of new medicine for the treatment of several diseases.
Anticancer drugs , Curcuma longa , Curcumin , drug resistance , Medicinal plants
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Department of Eastern Medicine, Government College University Faisalabad, Pakistan
Department of Biochemistry, Government College University Faisalabad, Pakistan
Department of Allied Health Sciences, Sargodha Medical College, University of Sargodha, Sargodha, Pakistan
V. M. Gorbatov Federal Research Center for Food Systems of RussianAcademy of Sciences, Moscow, Russian Federation
Prokhorov General Physics Institute, Russian Academy of Sciences, Moscow, Russian Federation
K.G. Razumovsky Moscow State University of Technologies and Management (the First Cossack University), Moscow, Russian Federation
Shakarim State University of Semey, Semey, Kazakhstan
Department of Chemistry, University of Swabi, Swabi, Anbar, KPK, Pakistan
Institute of Research and Development, Duy Tan University, Da Nang, 550000, Viet Nam
Faculty of Environment and Chemical Engineering, Duy Tan University, Da Nang, 550000, Viet Nam
Indigenous Knowledge Systems Centre, Faculty of Natural and Agricultural Sciences, North-West University, Private Bag X2046, Mmabatho, 2745, North West Province, South Africa
Department of Eastern Medicine
Department of Biochemistry
Department of Allied Health Sciences
V. M. Gorbatov Federal Research Center for Food Systems of RussianAcademy of Sciences
Prokhorov General Physics Institute
K.G. Razumovsky Moscow State University of Technologies and Management (the First Cossack University)
Shakarim State University of Semey
Department of Chemistry
Institute of Research and Development
Faculty of Environment and Chemical Engineering
Indigenous Knowledge Systems Centre
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