Santalum Genus: Phytochemical constituents, biological activities and health promoting-effects


Sharifi-Rad J. Quispe C. Turgumbayeva A. Mertdinç Z. Tütüncü S. Aydar E.F. Özçelik B. Anna S.-W. Mariola S. Koziróg A. Otlewska A. Antolak H. Sen S. Acharya K. Lapava N. Emamzadeh-Yazdi S. Martorell M. Kumar M. Varoni E.M. Iriti M. Calina D.
1 January 2023De Gruyter Open Ltd

Zeitschrift fur Naturforschung - Section C Journal of Biosciences
2023#78Issue 1-29 - 25 pp.

Santalum genus belongs to the family of Santalaceae, widespread in India, Australia, Hawaii, Sri Lanka, and Indonesia, and valued as traditional medicine, rituals and modern bioactivities. Sandalwood is reported to possess a plethora of bioactive compounds such as essential oil and its components (α-santalol and β-santalol), phenolic compounds and fatty acids. These bioactives play important role in contributing towards biological activities and health-promoting effects in humans. Pre-clinical and clinical studies have shown the role of sandalwood extract as antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, neuroleptic, antihyperglycemic, antihyperlipidemic, and anticancer activities. Safety studies on sandalwood essential oil (EO) and its extracts have proven them as a safe ingredient to be utilized in health promotion. Phytoconstituents, bioactivities and traditional uses established sandalwood as one of the innovative materials for application in the pharma, food, and biomedical industry.

bioactivities , clinical studies , essential oil , phytochemistry , safety , sandalwood

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Facultad de Medicina, Universidad Del Azuay, Cuenca, Ecuador
Facultad de Ciencias de la Salud, Universidad Arturo Prat, Avda. Arturo Prat 2120, Iquique, 1110939, Chile
Higher School of Medicine, Al-Farabi Kazakh National University, Almaty, Kazakhstan
School of Pharmacy, JSC S. D. Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
Faculty of Chemical and Metallurgical Engineering, Department of Food Engineering, Istanbul Technical University, Maslak, Istanbul, 34469, Turkey
BIOACTIVE Research & Innovation Food Manufacturing Industry Trade LTD Co., Istanbul 34469, Maslak, Turkey
Department of Forage Crop Production, Institute of Soil Science and Plant Cultivation - State Research Institute, Czartoryskich 8, 24-100, Puławy, Poland
Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Institute of Fermentation Technology and Microbiology, Wolczanska 171/173, 90 - 924, Lodz, Poland
Molecular and Applied Mycology and Plant Pathology Laboratory, Department of Botany, University of Calcutta, 700019, Kolkata, India
Department of Botany, Fakir Chand College, Diamond Harbour, West Bengal, 743331, India
Medicine Standartization Department of Vitebsk State Medical University, Vitebsk, Belarus
Department of Plant and Soil Sciences, University of Pretoria, Pretoria, Gauteng, 0002, South Africa
Department of Nutrition and Dietetics, Faculty of Pharmacy, Centre for Healthy Living, University of Concepción, Concepción, 4070386, Chile
Universidad de Concepción, Unidad de Desarrollo Tecnológico, UDT, Concepción, 4070386, Chile
Chemical and Biochemical Processing Division, ICAR - Central Institute for Research on Cotton Technology, Mumbai, 400019, India
Department of Biomedical, Surgical and Dental Sciences, Università Degli Studi di Milano, Milano, 20133, Italy
National Interuniversity Consortium of Materials Science and Technology (INSTM), Firenze, 50121, Italy
Department of Agricultural and Environmental Sciences, Università Degli Studi di Milano, Milano, 20133, Italy
Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, Craiova, 200349, Romania

Facultad de Medicina
Facultad de Ciencias de la Salud
Higher School of Medicine
School of Pharmacy
Faculty of Chemical and Metallurgical Engineering
BIOACTIVE Research & Innovation Food Manufacturing Industry Trade LTD Co.
Department of Forage Crop Production
Faculty of Biotechnology and Food Sciences
Molecular and Applied Mycology and Plant Pathology Laboratory
Department of Botany
Medicine Standartization Department of Vitebsk State Medical University
Department of Plant and Soil Sciences
Department of Nutrition and Dietetics
Universidad de Concepción
Chemical and Biochemical Processing Division
Department of Biomedical
National Interuniversity Consortium of Materials Science and Technology (INSTM)
Department of Agricultural and Environmental Sciences
Department of Clinical Pharmacy

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