Honey Phytochemicals: Bioactive Agents With Therapeutic Potential for Dermatological Disorders
McLoone P. Oladejo T.O. Kassym L. McDougall G.J.
December 2024John Wiley and Sons Ltd
Phytotherapy Research
2024#38Issue 125741 - 5764 pp.
Honey has been reported to have a range of biological activities including antimicrobial, immunomodulatory, and wound healing effects. Indeed, medical-grade honey is currently used in hospitals for the clinical management of wound infections. Honey is also of scientific interest for its therapeutic effects on other dermatological disorders such as atopic dermatitis, rosacea, and skin cancer. Recent studies have uncovered that honey contains a range of phytochemicals including flavonoids, dicarboxylic acids, coumarins, and phenolic acids. In this review, PubMed was used to search the scientific literature on the biological properties of honey phytochemicals in relation to dermatological disorders and to evaluate their potential as bioactive agents, drugs, or cosmeceuticals for the treatment of skin disease. The review revealed that phytochemicals found in honey have antimicrobial, anti-inflammatory, antiaging, antioxidant, anticancer, depigmenting, photoprotective, wound healing, and skin barrier enhancing properties. Although further high-quality studies are required to establish clinical efficacy, these findings suggest that honey phytochemicals may have the potential to be used as bioactive agents for the management of a range of dermatological disorders including wounds, psoriasis, atopic dermatitis, vitiligo, rosacea, and skin cancer.
dermatological disorders , honey , phytochemicals , skin
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School of Medicine, University of Kurdistan Hewlêr, Erbil, Iraq
School of Molecular Biosciences, University of Glasgow, Glasgow, United Kingdom
Department of Biomedical Sciences, Nazarbayev University School of Medicine, Astana, Kazakhstan
Department of General Medical Practice With a Course of Evidence-Based Medicine, NJSC, Astana Medical University, Astana, Kazakhstan
Plant Biochemistry and Food Quality Group, Environmental and Biochemical Sciences Department, The James Hutton Institute, Dundee, United Kingdom
School of Medicine
School of Molecular Biosciences
Department of Biomedical Sciences
Department of General Medical Practice With a Course of Evidence-Based Medicine
Plant Biochemistry and Food Quality Group
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026