Phytochemical Insights and Therapeutic Potential of Chamaenerion angustifolium and Chamaenerion latifolium
Kozhantayeva A. Iskakova Z. Ibrayeva M. Sapiyeva A. Arkharbekova M. Tashenov Y.
March 2025Multidisciplinary Digital Publishing Institute (MDPI)
Molecules
2025#30Issue 5
The Chamaenerion genus, particularly Chamaenerion angustifolium and Chamaenerion latifolium, is recognized for its rich phytochemical composition and extensive medicinal properties. These species are abundant in polyphenols, flavonoids, and tannins, which contribute to their potent antioxidant, antimicrobial, and anticancer activities. This review provides a comprehensive analysis of their phytochemical constituents, with an emphasis on how processing methods, including fermentation, influence bioactivity. Notably, fermentation enhances the levels of key bioactive compounds, such as oenothein B, gallic acid, and ellagic acid, thereby increasing their pharmacological potential. Additionally, this review evaluates the biological activities of Chamaenerion species in relation to their chemical composition, while also considering the limitations of current studies, such as the lack of in vivo or clinical trials. The literature for this review was sourced from scientific databases, including PubMed, Scopus, and ScienceDirect, covering research from 2010 to 2024. Future studies should focus on optimizing extraction methods, elucidating synergistic bioactivities, and conducting in-depth clinical trials to validate their efficacy and safety.
antimicrobial , antioxidant activity , antiproliferative , Chamaenerion angustifolium , Chamaenerion latifolium , oenothein B , phytochemicals
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Research Institute of New Chemical Technologies, L.N. Gumilyov, Eurasian National University, Satpayev Street 2, Astana, 010000, Kazakhstan
Department of Chemistry, Faculty of Natural Sciences, L.N. Gumilyov, Eurasian National University, Satpayev Street 2, Astana, 010000, Kazakhstan
Faculty of Science and Technology, Yessenov University, Aktau, 130000, Kazakhstan
Department of General and Biological Chemistry, NJSC “Astana Medical University”, Astana, 010000, Kazakhstan
Research Institute of New Chemical Technologies
Department of Chemistry
Faculty of Science and Technology
Department of General and Biological Chemistry
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