Edible Nanocoating of Dextran/Lipid and Curcumin for Enhanced Shelf Life of Fresh Produce
Kabdrakhmanova S. Augustine R. Sathian A. Thomas A. Joseph T.M. Kalarikkal N. Ibraeva Z. Madiyar B. Thomas S. Hasan A. Joshy K.S.
15 December 2025John Wiley and Sons Inc
Journal of Polymer Science
2025#63Issue 245414 - 5425 pp.
The purpose of the present study was to develop a nano-coating for fresh vegetables and fruits using a combination of curcumin, sesame oil, stearic acid, and dextran (CSSDNs). The anti-bacterial and nontoxic nature of nanoparticles were tested against Gram-positive bacteria (Staphylococcusaureus) and human fibroblast cells. Enhanced aqueous solubility of curcumin and its stability in the bloodstream were observed from the in vitro blood compatibility studies. The anti-cancer activity of curcumin-loaded nanoparticles was tested against SK-BR3 cells, demonstrating excellent antitumor activity. These findings indicate that the CSSDNs system can be used as an edible coating with strong antibacterial properties and as an effective means of delivering curcumin, which has proven to be successful in treating or preventing cancer.
curcumin , dextran , nano-coating , nanodispersion
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Satbayev University, Almaty, Kazakhstan
Scientific Center of Composite Materials, Almaty, Kazakhstan
Department of Radiology, Stanford Medicine, Stanford University, Doha, Qatar
Biomedical Research Center (BRC), Qatar University, Doha, Qatar
College of Science and Engineering, James Cook University, Townsville, QLD, Australia
Department of Chemistry, Bishop Chulaparambil Memorial College, Kerala, Kottayam, India
Department of Polymer Technology, Faculty of Chemistry, Gdansk University of Technology, Gdańsk, Poland
School of Pure and Applied Physics, Mahatma Gandhi University, Kerala, Kottayam, India
Abai Kazakh National Pedagogical University, Almaty, Kazakhstan
School of Nanoscience and Nanotechnology, Mahatma Gandhi University, Kerala, Kottayam, India
Department of Mechanical and Industrial Engineering, Qatar University, Doha, Qatar
Satbayev University
Scientific Center of Composite Materials
Department of Radiology
Biomedical Research Center (BRC)
College of Science and Engineering
Department of Chemistry
Department of Polymer Technology
School of Pure and Applied Physics
Abai Kazakh National Pedagogical University
School of Nanoscience and Nanotechnology
Department of Mechanical and Industrial Engineering
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