MODERN METHODS OF INTRAOPERATIVE FLUORESCENT IMAGING OF THE PARATHYROID GLANDS IN ENDOCRINE SURGERY: A LITERARY REVIEW

МЕТОДЫ ИНТРАОПЕРАЦИОННОЙ ФЛУОРЕСЦЕНТНОЙ ТОПИЧЕСКОЙ ДИАГНОСТИКИ ПАРАЩИТОВИДНЫХ ЖЕЛЕЗ: ЛИТЕРАТУРНЫЙ ОБЗОР
Zinchenko S.V. Shanazarov N.A. Muratov N.F. Kisikova S.D. Seitbekova K.S. Galiev I.Z. Ibragim M.I. Ahmetshin R.R.
2025 Russian Photodynamic Association

Biomedical Photonics
2025 #14 Issue 1 47 - 52 pp.

Hyperparathyroidism (primary, secondary and tertiary) is a common endocrine disease, often occurring with pronounced symptoms, in most cases caused by adenoma (rarely several adenomas) in primary hyperparathyroidism (pHPT) and chronic renal failure in patients on programmed hemodialysis with secondary (sHPT) and tertiary (tHPT) hyperparathyroidism. To date, the only radical treatment for hyperparathyroidism (HPT) is surgical removal of pathologically altered parathyroid glands. In this regard, there is a need to improve diagnostic search algorithms, including intraoperative ones, for altered parathyroid glands. The main objective of the review is to study current trends and techniques of intraoperative imaging of the parathyroid glands, compare these methods and evaluate their effectiveness. The use of qualitatively new technologies for the topical diagnosis of altered parathyroid glands, such as identification by autofluorescence in the near infrared spectrum (NIRAF), the technique of using indocyanine green (ICG) and 5-aminolevulinic acid under UV radiation, make it possible to visualize the localization of the parathyroid glands with more than 90% accuracy. However, the issue of their priority use remains open and unresolved.

5-ALA , ICG , imaging , NIRAF , parathyroid gland , primary , secondary , surgical treatment , tertiary hyperparathyroidism

Text of the article Перейти на текст статьи

Kazan (Volga Region) Federal University, Kazan, Russian Federation
Medical Centre Hospital of the President’s Affairs Administration of the Republic of Kazakhstan RSE, Astana, Kazakhstan
MC Aya, Astana, Kazakhstan

Kazan (Volga Region) Federal University
Medical Centre Hospital of the President’s Affairs Administration of the Republic of Kazakhstan RSE
MC Aya

10 лет помогаем публиковать статьи Международный издатель

Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026