Epidemiological and Molecular-Genetic Characteristics of the Measles Outbreak in Kazakhstan
Zhuzzhasarova A. Bayesheva D. Azimbaeva N. Smagul M. Nusupbaeva G. Turdalina B. Seidullayeva A. Abdullaev B. Kushugulova A.
April 2022Modestum LTD
Electronic Journal of General Medicine
2022#19Issue 2
Introduction: Genetic characterization of measles viruses (MVs) is an important component of laboratory surveillance of measles. In this study, a phylogenetic analysis was performed of the nucleoprotein gene sequences isolated in the Republic of Kazakhstan in 2018 year. Objective: To study the epidemiological characteristics of measles and identify the circulating strain in the Republic of Kazakhstan during the period of increasing incidence for 36 global efforts to eliminate measles among the population. Material and Methods: On the basis of the reference laboratory “Center for Sanitary and Epidemiological Expertise and Monitoring” of the RSE at the PEM “NCPH” genotyping of measles virus isolated from biological material (urine) from laboratory-confirmed cases was performed. Results: According to the results of the study, it was revealed that the genotypes of the measles virus circulating in the Republic of Kazakhstan belong to two genotypes, the majority of samples (n=16) belonged to the D8genotype and2 samplesto the B3 genotype/MVi/Harare.ZWE/38.09./.
Children , Genotyping , Measles , Republic of Kazakhstan
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Non-Profit Joint-Stock Company “Medical University of Astana”, Nur-Sultan, Kazakhstan
Department of the Public Health Protection Committee of the Ministry of Health of the Republic of Kazakhstan, Nur-Sultan, Kazakhstan
Department of Infectious and Parasitic Diseases of the National Center of Public Health, Nur-Sultan, Kazakhstan
“Center for Sanitary and Epidemiological Expertise and Monitoring” of the RSE at the PEM “NCPH”, Almaty, Kazakhstan
City Multidisciplinary Hospital No 1 of the Government of Nur-Sultan, Nur-Sultan, Kazakhstan
National Laboratory Astana Nazarbayev University, Nur-Sultan, Kazakhstan
Kazakhstan Society of Human Microbiome Researchers, Nur-Sultan, Kazakhstan
Non-Profit Joint-Stock Company “Medical University of Astana”
Department of the Public Health Protection Committee of the Ministry of Health of the Republic of Kazakhstan
Department of Infectious and Parasitic Diseases of the National Center of Public Health
“Center for Sanitary and Epidemiological Expertise and Monitoring” of the RSE at the PEM “NCPH”
City Multidisciplinary Hospital No 1 of the Government of Nur-Sultan
National Laboratory Astana Nazarbayev University
Kazakhstan Society of Human Microbiome Researchers
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