Component composition of essential oil of Rhodiola algida (Ledeb.) Fisch & C.A. Mey and its biological activity
Zhumagul M.Zh. Kubentayev S.A. Kurmanbayeva M.S. Myrzagaliyeva A.B. Suleimen R.N. Suleimen Y.M. Samarkhanova D.
30 June 2023al-Farabi Kazakh State National University
International Journal of Biology and Chemistry
2023#16Issue 1113 - 127 pp.
For the first time the component composition of essential oil of Rhodiola algida (Ledeb.) Fisch & C.A. Mey. family Crassulaceae, collected in places of natural growth in July 2020 in the Kazakh Altai was studied. The component composition of essential oil of this species was determined by gas chromatography and chromatography-mass spectrometry. The method of chromatography-mass spectrometry detected 100 components, of which 79 substances were identified, accounting for 82-83% of the total essential oil. Antioxidant activity was determined by the FRAP method. R. algida essential oil showed low antioxidant activity compared with butyl hydroxyanisole (BHA) at concentrations of 0.25-1.0 mg/ml, confirming the antioxidant properties of R. algida. Based on the results of cytotoxic activity against Artemia salina L. larvae, it was concluded that R. algida essential oil has good lethal toxicity at all concentrations tested, which proves the cytotoxicity of R. algida. At present, studies of R. algida based on substances from this plant and methods of their analysis are of direct interest for phytopreparation.
antioxidant activity , components , essential oils , Rhodiola algida
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Astana International University, Astana, Kazakhstan
Astana Botanical Garden, Institute of Botany and Phytoinroduction, Astana, Kazakhstan
Al-Farabi Kazakh National University, Almaty, Kazakhstan
Eurasian National University, Astana, Kazakhstan
Kazakh University of Technology and Business, Astana, Kazakhstan
Sh. Ualikhanov Kokshetau University, Kokshetau, Kazakhstan
Nazarbayev University, Astana, Kazakhstan
Astana International University
Astana Botanical Garden
Al-Farabi Kazakh National University
Eurasian National University
Kazakh University of Technology and Business
Sh. Ualikhanov Kokshetau University
Nazarbayev University
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