Development of Novel Composite Biocompatible Materials by Surface Modification of Porous Inorganic Compounds Using Bambus[6]Uril
Zhumabayeva G. Turebayeva P. Ukhov A. Fedorishin D. Gubankov A. Luchsheva V. Kurzina I. Bakibaev A. Ryskaliyeva R. Abdullina G. Bolysbekova S. Yerkassov R.
December 2023Multidisciplinary Digital Publishing Institute (MDPI)
Materials
2023#16Issue 23
In this present investigation, a novel series of composite materials based on porous inorganic compounds—hydroxyapatite and diatomite—have been innovatively formulated for the first time through surface modification employing the promising macromolecular compound, bambus[6]uril. The process entailed the application of a bambus[6]uril dispersion in water onto the surfaces of hydroxyapatite and diatomite. Extensive characterization was carried out, involving IR spectroscopy and SEM. The materials underwent assessment for hemolytic effects and plasma protein adsorption. The results revealed that materials containing surface-bound bambus[6]uril did not demonstrate inherent hemolytic effects, laying a robust groundwork for their use as biocompatible materials. These findings hold significant promise as an alternative pathway for the development of durable and efficient bio-composites, potentially unveiling supramolecular strategies incorporating encapsulated bambus[6]urils in analogous processes.
bambus[6]urils , biocompatible materials , diatomite , hemolytic effect , hydroxyapatite , plasma protein adsorption
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Department of Chemistry, L.N. Gumilyov Eurasian National University, Astana, 010000, Kazakhstan
Faculty of Chemistry, National Research Tomsk State University, Tomsk, 634028, Russian Federation
Faculty of Chemistry and Chemical Technology, Department of General and Inorganic Chemistry, Al-Farabi Kazakh National University, Almaty, 050000, Kazakhstan
Faculty of Engineering, Department of Mechanics and Oil and Gas Engineering, Toraigyrov University, Pavlodar, 140008, Kazakhstan
Higher School of Scientific Research, Astana International University, Astana, 010000, Kazakhstan
Department of Chemistry
Faculty of Chemistry
Faculty of Chemistry and Chemical Technology
Faculty of Engineering
Higher School of Scientific Research
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