Phytochemical studies of white mulberry fruits (Morus alba L.)
Zhumabayev N. Zhakipbekov K. Zhumabayev N. Datkhayev U. Tulemissov S.
February 2024Springer Science and Business Media Deutschland GmbH
Naunyn-Schmiedebergs Archives of Pharmacology
2024#397Issue 2807 - 815 pp.
Medicinal preparations made from plant materials have been widely used for many years due to their high pharmacological efficacy and safety of use. Therefore, a study of white mulberry fruits (Morus alba L.) for the content of substances is very important for the pharmaceutical industry such as flavonoids, alkaloids, polysaccharides, minerals, vitamins, and amino acids. White mulberry has a wide distribution area around the world, including in Kazakhstan, especially in the southern regions of the country (Almaty, Zhambyl, and Turkestan regions). The composition of the fruits of this plant is significantly influenced by the area where the trees grow, and therefore, the establishment of a specific composition of biologically active substances is very important. In the course of this study, such methods as gas chromatography were used—mass spectrometry of an extract obtained using carbon dioxide under subcritical conditions, atomic absorption, gravimetric, and spectrophotometric methods. As a result, for the first time in Kazakhstan, the composition of white mulberry fruits (Morus alba L.), namely, biologically active substances, has been identified, such as alkaloids, flavonoids, vitamins, macro- and microelements, and amino acids and fatty acids; in addition, the percentage composition of the above compounds has been determined. The results of the study show a comparative analysis of the component composition of white mulberry fruits (Morus alba L.) in various areas of tree growth, including outside of Kazakhstan. The obtained data testify to the great possibilities of using this raw material in medicine, pharmacology, and the food industry.
Atomic absorption , Biologically active substances , Fluorometric method , Gas chromatography , Spectrophotometric
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Department of Organization and Management and Economics of Pharmacy and Clinical Pharmacy, Asfendiyarov Kazakh National Medical University, 94 Tole Bi Str., Almaty, 050000, Kazakhstan
Department of Organization and Management of Pharmaceutical Business, South Kazakhstan Medical Academy, 160019, 1 Al-Farabi Sq., Shymkent, Kazakhstan
LLP “Zhanga Shipa”, 17/1 Dysenbai Altynbekov Str., Shymkent, 160700, Kazakhstan
Department of Organization and Management and Economics of Pharmacy and Clinical Pharmacy
Department of Organization and Management of Pharmaceutical Business
LLP “Zhanga Shipa”
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