Green Extraction of Plant Materials Using Supercritical CO2: Insights into Methods, Analysis, and Bioactivity


Yıldırım M. Erşatır M. Poyraz S. Amangeldinova M. Kudrina N.O. Terletskaya N.V.
August 2024Multidisciplinary Digital Publishing Institute (MDPI)

Plants
2024#13Issue 16

In recent years, the supercritical CO2 extraction method has gained attention due to its use of environmentally friendly, non-toxic solvents, ability to operate at lower temperatures that do not cause the degradation of bioactive compounds, and capacity for rapid extraction. This method is particularly notable for isolating bioactive compounds from plants. The extracts obtained have shown superior properties due to their activity against diseases such as cancer, which is one of the leading causes of death worldwide. The aim of this study is to provide an in-depth understanding of the supercritical CO2 extraction method, as well as to discuss its advantages and disadvantages. Furthermore, the study includes specific data on various plant materials, detailing the following parameters: plant name and region, bioactive compounds or compound classes, extraction temperature (°C), pressure (bar), time (minutes), co-solvent used, and flow rate. Additionally, this study covers extensive research on the isolation of bioactive compounds and the efficacy of the obtained extracts against cancer.

anticancer activity , extraction , green chemistry , medicinal plants , supercritical carbon dioxide , supercritical fluid

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Department of Biochemistry, Faculty of Pharmacy, Harran University, Sanliurfa, 63050, Turkey
Department of Chemistry, Faculty of Art and Science, Cukurova University, Adana, 01330, Turkey
Nevşehir, 50040, Turkey
Department of Biodiversity and Biological Resources, Faculty of Biology and Biotechnology, Al-Farabi Kazakh National University, Al-Farabi Av., 71, Almaty, 050040, Kazakhstan
Institute of Genetic and Physiology, Al-Farabi Av., 93, Almaty, 050040, Kazakhstan

Department of Biochemistry
Department of Chemistry
Nevşehir
Department of Biodiversity and Biological Resources
Institute of Genetic and Physiology

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