Myringoplasty with morphological rationale of application of xenoperitoneum decellularized matrix in experiment
Yesniyazov D. Maida T. Abatov N. Yukhnevich Y. Badyrov R.
2021Scientific Foundation SPIROSKI
Open Access Macedonian Journal of Medical Sciences
2021#9811 - 816 pp.
AIM: The aim of the study is to create a myringoplasty technique with decellularized matrix of xenoperitoneum in an experiment on rabbits with morphological rationale of a new biological material application. METHODS: Sixty rabbits were included in research. The animals were randomly divided into two groups for use the bioimplant-decellularized matrix of xenoperitoneum and control. Each subgroup corresponded to the observation period and the removal of the animal from the experiment. Observation period was 7 days, 21 days, and 30 days after myringoplasty. RESULTS: The maturation of connective tissue in both groups was completed by the 30th day. However, the change in the exudative phase into the proliferative phase occurred faster and the dynamics of reparative processes after myringoplasty was better in experimental group. CONCLUSION: The use of the decellularized matrix of xenoperitoneum had better reparative properties.
Biological implant , Decellularized matrix , Myringoplasty , Tympanic membrane perforation , Xenoperitoneum
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Department of Surgical Diseases, Karaganda Medical University, Karaganda, Kazakhstan
Department of Surgical Diseases
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