Anthelmintic Efficacy of Complex Herbal Preparations and their Effect on Hematological Parameters in Sheep
Yertleuova B. Sidikhov B. Karmaliyev R. Nurzhanova F. Zakirova F. Ichshanova A. Terletskaya N.
January-February 2026Unique Scientific Publishers
International Journal of Veterinary Science
2026#15Issue 118 - 24 pp.
Gastrointestinal helminthiases are among most widespread and economically important diseases of small ruminants. It can lead to retardation in growth, reduced productivity, and significant financial losses. In Kazakhstan, infestation rates in sheep often exceed 79%. The complete reliance on chemical anthelmintics have created concerns of drug resistance, residues, and environmental impacts. These challenges highlight urgent need for effective, safe, and eco-friendly alternatives. Medicinal plants represent a promising solution but comprehensive in vivo studies under natural infection conditions remain limited. Our study investigates the in-vivo anthelmintic efficacy of a complex of medicinal plants Artemisia absinthium, Artemisia lerchiana, Hypericum perforatum, Bidens tripartita, and Chelidonium majus. The clinical and parasitological tests were conducted on 40 sheep having the age between 1–2 years, spontaneously infected with Moniezia and Strongylata. The infestation was assessed by helminth egg counts in VIGIS chamber. The effectiveness of preparations was evaluated 14 days after the administration in terms of the prevalence efficacy and intensity efficacy. The results of control and critical tests showed high anthelmintic efficacy against gastrointestinal helminthic diseases in sheep. Complex herbal preparation 1 achieved 90% IE and 90% PE against Moniezia, and 95% IE and 90% PE against strongylata. These results were found comparable to standard albendazole-based drug Alvet. The second complex herbal preparation 2 showed 80.5% IE and 80% PE against Moniezia, and 90.2% IE with 80% PE against strongylata. The other hematological and biochemical parameters were found with in normal values and bactericidal activity of serum was found increased in treated groups. The findings highlight potential of plant-based formulations as effective and eco-friendly alternatives to synthetic anthelmintics.
Anthelmintic efficacy , Common wormwood , Greater celandine , In-vivo method , Lerches wormwood , Perforate St. Johns wort , Three-part beggar ticks
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Non-profit JSC Zhangir Khan West Kazakhstan Agrarian and Technical University, Uralsk, 090009, Kazakhstan
Institute of Genetic and Physiology, Al-Farabi 93, Almaty, 050040, Kazakhstan
Non-profit JSC Zhangir Khan West Kazakhstan Agrarian and Technical University
Institute of Genetic and Physiology
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Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026