Advance in the Diagnostics of Mare Pregnancy and Assessing the Activity of Gonadotropin in Serum of in-Foal Mare

Yerkekulova K.K. Alibayev N. Yuldashbayev Y.A. Alikhanov O. Beketauov O. Baimukanov D.A.
2024 Science Publications

OnLine Journal of Biological Sciences
2024 #24 Issue 3 395 - 402 pp.

Research works on the improvement of mare pregnancy diagnostics and evaluation of biological activity of gonadotropic preparation based on the use of enzyme-linked immunosorbent assay were carried out. As the result of diagnostics and evaluation, effective producers as donors for obtaining gonadotropic preparation among the Kazakh population of mares with type “zhabe”, the animal units of 60 days with their 5-6 year pregnancy containing FSH-10,38±0,65 mIU/1 mL and 7-8-year-old with FSH content-10,50±0,32 mIU/1 mL; 70 days of their 3-4-year-old pregnancy with FSH content-10,52±0,21 mIU/1 mL, 5-6-year-old with FSH content-11,34±0,45 mIU/1mL, 7-8-year-old with FSH content-11,34±0,32 mIU/1 mL, 9-10-year-old with FSH content-11,06±0,29 mIU/1 mL are identified. A new method for the selection of a drug by biological activity based on the content of follicle-stimulating hormone level for a given herd was developed, which allows to determination of the activity in international units, without the traditional, labor-consuming, outdated method for determination using laboratory white mice, addressing ethical issues in research.

Blood Sample , Follicle-Stimulating Hormone , Gonadotropic Hormone , Gonadotropic Hormone Activity , Luteinizing Hormone , Mare , Mare Age , Producer

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Agricultural Biotechnology Research Laboratory, M. Auezov South Kazakhstan University, Shymkent, Kazakhstan
Department of Private Animal Science, Russian State Agrarian University, Moscow Timiryazev Agricultural Academy, Moscow, Russian Federation
Department of Animal Husbandry, Veterinary Medicine and Feed and Milk Quality Assessment, Scientific and Production Center for Animal Husbandry and Veterinary, Astana, Kazakhstan

Agricultural Biotechnology Research Laboratory
Department of Private Animal Science
Department of Animal Husbandry

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