Metabolomic adaptations and genetic polymorphism in ecopopulations of Rhodiola linearifolia Boriss
Yerbay M. Khapilina O.N. Turzhanova A.S. Otradnykh I.G. Sedina I.A. Mamirova A. Korbozova N.K. Magzumova S. Ashimuly K. Kudrina N.O. Salnikov V.G. Terletskaya N.V.
2025Frontiers Media SA
Frontiers in Plant Science
2025#16
Rhodiola linearifolia Boriss. (R. linearifolia) has long been used in folk medicine; however, research on its resources is limited due to the species inaccessibility for collection, and its potential for cultivation has not been previously explored. Understanding the synthesis of its valuable metabolites, as well as the factors influencing their accumulation under natural conditions, remains a relevant research objective. In this study, the metabolome of various ecopopulations of R. linearifolia was analyzed, and the relationship between metabolomic variations and genetic polymorphism was investigated using inter-simple sequence repeat (ISSR) and inter-primer binding site (iPBS) markers. Several significant positive correlations (r = 0.50–0.89) were observed. Significant genetic and metabolomic differences were identified among ecopopulations. Notably, experimental confirmation was obtained showing that ecopopulations with higher genetic polymorphism exhibited a more diverse metabolomic profile. These findings contribute to a deeper understanding of the species’ adaptation mechanisms and provide a foundation both for developing approaches to in situ conservation for R. linearifolia in situ in natural habitats, and optimizing introduction strategies for cultivation outside its natural range. Copyright
ecopopulations , iPBS amplification profiling , ISSR amplification profiling , metabolome , polymorphism , R. linearifoliaBoriss
Text of the article Перейти на текст статьи
Faculty of Biology and Biotechnology, Al-Farabi Kazakh National University, Almaty, Kazakhstan
Institute of Genetic and Physiology, Almaty, Kazakhstan
National Center for Biotechnology, Astana, Kazakhstan
Institute of Botany and Phytointroduction, Almaty, Kazakhstan
Faculty of Chemistry, Al-Farabi Kazakh National University, Almaty, Kazakhstan
Faculty of Geografy, Al-Farabi Kazakh National University, Almaty, Kazakhstan
Faculty of Biology and Biotechnology
Institute of Genetic and Physiology
National Center for Biotechnology
Institute of Botany and Phytointroduction
Faculty of Chemistry
Faculty of Geografy
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026