ASSOCIATION BETWEEN TREATMENT OUTCOME AND AGE IN TUBERCULOSIS AND DIABETES PATIENTS: A POPULATION ANALYSIS


СВЯЗЬ МЕЖДУ ИСХОДОМ ЛЕЧЕНИЯ И ВОЗРАСТОМ У ПАЦИЕНТОВ С ТУБЕРКУЛЕЗОМ И САХАРНЫМ ДИАБЕТОМ: ПОПУЛЯЦИОННЫЙ АНАЛИЗ
Yeraliyeva L.T. Issayeva A.M.
2023Endocrinology Research Centre

Problemy Endokrinologii
2023#69Issue 593 - 98 pp.

BACKGROUND: The undoubted importance of this work lies in the fact that for the first time in the Republic of Kazakhstan, an analysis is being made of the relationship between age and treatment outcome in patients with a comorbid diagnosis of tuberculosis and diabetes mellitus. AIM: Identification of the correlation between the age of patients and the outcome of treatment in patients with tuberculosis and diabetes mellitus. MATERIALS AND METHODS: Cross-sectional retrospective study of 2,125 patients with TB and diabetes mellitus out of a total of 43,807 of all patients diagnosed with TB (2017–2019). The study analyzed the data of patients with comorbidity from all regions of Kazakhstan (data from 14 regions and 3 cities of republican significance) (2017–2019). RESULTS: A high prevalence of tuberculosis morbidity with a concomitant diagnosis of diabetes mellitus in the age group from 45 to 64 years was revealed. This group consisted of 1193 patients out of 2115 (56.4% of the total number of patients with tuberculosis and diabetes mellitus). The average age of all studied patients with DM was 54.7±13.4 years. There is a positive correlation between age and treatment outcome in TB patients. Mortality was higher in the age group over 45 years old — OR95%CI = 0.213 [0.019–2.362], p — 0.0000015 (p < 0.05). CONCLUSION: As a result of the study for 2017–2019, material was obtained, the analysis of which made it possible to conclude that the outcome of treatment in the form of mortality is directly proportional to the patient’s age. Those. older age groups are more likely to die than younger patients.

diabetes mellitus , Kazakhstan , mortality , treatment outcome , tuberculosis

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Kazakh National Medical University» named after S.D. Asfendiyarov, Almaty, Kazakhstan
National Scientific Center for Phthisiopulmonology of the Republic of Kazakhstan, Almaty, Kazakhstan

Kazakh National Medical University» named after S.D. Asfendiyarov
National Scientific Center for Phthisiopulmonology of the Republic of Kazakhstan

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