Emerging nanotechnologies for targeting antimicrobial resistance


Weldick P.J. Wang A. Halbus A.F. Paunov V.N.
2 March 2022Royal Society of Chemistry

Nanoscale
2022#14Issue 114018 - 4041 pp.

Antimicrobial resistance is a leading cause of mortality worldwide. Without newly approved antibiotics and antifungals being brought to the market, resistance is being developed to the ones currently available to clinicians. The reason is the applied evolutionary pressure to bacterial and fungal species due to the wide overuse of common antibiotics and antifungals in clinical practice and agriculture. Biofilms harbour antimicrobial-resistant subpopulations, which make their antimicrobial treatment even more challenging. Nanoparticle-based technologies have recently been shown to successfully overcome antimicrobial resistance in both planktonic and biofilms phenotypes. This results from the combination of novel nanomaterial research and classic antimicrobial therapies which promise to deliver a whole new generation of high-performance active nanocarrier systems. This review discusses the latest developments of promising nanotechnologies with applications against resistant pathogens and evaluates their potential and feasibility for use in novel antimicrobial therapies.



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Department of Chemistry and Biochemistry, University of Hull, Hull, HU6 7RX, United Kingdom
Department of Chemistry, College of Science, University of Babylon, Hilla, Iraq
Department of Chemistry, Nazarbayev University, Kabanbay Baryr Ave. 53, Nur-sultan city, 010000, Kazakhstan

Department of Chemistry and Biochemistry
Department of Chemistry
Department of Chemistry

10 лет помогаем публиковать статьи Международный издатель

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