Quality of life in heart failure. the heart of the matter. A scientific statement of the Heart Failure Association and the European Association of Preventive Cardiology of the European Society of Cardiology
Volterrani M. Halasz G. Adamopoulos S. Agostoni P.G. Butler J. Coats A.J.S. Cohen-Solal A. Doehner W. Filippatos G. Jankowska E. Lam C.S.P. Lambrinou E. Lund L.H. Rosano G. Metra M. Paolillo S. Perrone Filardi P. Rakisheva A. Savarese G. Seferovic P. Tocchetti C.G. Piepoli M.
1 August 2025Oxford University Press
European Journal of Preventive Cardiology
2025#32Issue 11912 - 925 pp.
For most patients with chronic, progressive illnesses, maintaining good quality of life (QoL), with preserved functional capacity, is just as crucial as prolonging survival. Patients with heart failure (HF) experience much worse QoL and effort intolerance than both the general population and people with other chronic conditions, since they present a range of physical and psychological symptoms, including shortness of breath, chest discomfort, fatigue, fluid congestion, trouble with sleeping, and depression. These symptoms reduce patients capacity for daily social and physical activity. Usual endpoints of large-scale trials in chronic HF have mostly been defined to evaluate treatments regarding hospitalizations and mortality, but more recently, patients priorities and needs expressed with QoL are gaining more awareness and are being more extensively evaluated. This scientific statement aims at discussing the importance of QoL in HF, summarizing the most largely adopted questionnaires in HF care, and providing an overview on their application in trials and the potential for their transition to clinical practice. Finally, by discussing the reasons limiting their application in daily clinical routine and the strategies that may promote their implementation, this statement aims at fostering the systematic integration of the patients standpoint in HF care.
Aging , Chronic disease , Exercise tolerance , Frailty , Functional capacity , Heart failure , Physical activity , Quality of life
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IRCCS San Raffaele Roma, Rome, 00166, Italy
San Raffaele Open University, Rome, Italy
Azienda Ospedaliera San Camillo-Forlanini, Rome, Italy
Onassion Hospital, Athens, Greece
Centro Cardiologico Monzino, IRCCS, Milan, Italy
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Baylor Scott and White Research Institute, Dallas, TX, United States
Department of Medicine, University of Mississippi, Jackson, MS, United States
Heart Research Institute, Sydney, Australia
Universite Paris Cite, France
Berlin Insititute of Health Center for Regenerative Therapies, Charite- Universitatsmedizin Berlin, Berlin, Germany
Center for Stroke Research Berlin, German Centre for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité, Department of Cardiology (Campus Virchow), Charite Universitatsmedizin Berlin, Germany
Department of Cardiology, Attikon University Hospital, School of Medicine, National and Kapodistrian University, Athens, Greece
University of Wroclaw, Poland
National Heart Centre, Singapore, Singapore
Duke-National University, Singapore, Singapore
Cyprus University of Technology, Cyprus
Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
Division of Cardiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
Heart and Vascular Theme, Karolinska University Hospital, Stockholm, Sweden
San Raffaele Cassino Hospital, Cassino, Italy
Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy
Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy
Cardiology Department, Scientific Institute of Cardiology and Internal Medicine, Almaty, Kazakhstan
University Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Serbian Academy of Arts and Sciences, Belgrade, Serbia
Department of Translational Medical Sciences (DISMET), Center for Basic and Clinical Immunology Research (CISI), Interdepartmental Center for Clinical and Translational Research (CIRCET), Interdepartmental Hypertension Research Center (CIRIAPA), Federico II University, Naples, Italy
Clinical Cardiology, IRCCS, Policlinico San Donato, San Donato Milanese, Via Morandi 30, Milan, 20097, Italy
Department of Biomedical Science for Health, University of Milan, Via Festa del Perdono, Milan, 20100, Italy
IRCCS San Raffaele Roma
San Raffaele Open University
Azienda Ospedaliera San Camillo-Forlanini
Onassion Hospital
Centro Cardiologico Monzino
Department of Clinical Sciences and Community Health
Baylor Scott and White Research Institute
Department of Medicine
Heart Research Institute
Universite Paris Cite
Berlin Insititute of Health Center for Regenerative Therapies
Center for Stroke Research Berlin
Deutsches Herzzentrum der Charité
Department of Cardiology
University of Wroclaw
National Heart Centre
Duke-National University
Cyprus University of Technology
Department of Medicine Solna
Division of Cardiology
Heart and Vascular Theme
San Raffaele Cassino Hospital
Cardiology
Department of Advanced Biomedical Sciences
Cardiology Department
University Faculty of Medicine
Serbian Academy of Arts and Sciences
Department of Translational Medical Sciences (DISMET)
Clinical Cardiology
Department of Biomedical Science for Health
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