Refractory gram-negative septic shock complicated by extended purpura fulminans and multiple organ failure in a 23-year-old puerpera
Viderman D. Umbetzhanov Y. Temirov T. Kuzkov V.V.
June 2021Korean Society of Anesthesiologists
Korean Journal of Anesthesiology
2021#74Issue 3266 - 270 pp.
Background: Pregnancy-related infections are the third most common cause of maternal death worldwide. The aim of this report is to present a case of pregnancy-related infection, which progressed into refractory septic shock accompanied by purpura fulminans and multiple organ failure. Case: A 23-year-old woman in the postpartum period developed fulminant, refractory septic shock complicated by purpura fulminans and multiple organ failure syndrome (acute respiratory distress syndrome, acute kidney injury, and encephalopathy). Management included antibacterial therapy, fluid and transfusion therapy, nutritional support, protective mechanical ventilation, hydrocortisone, a large dose of ascorbic acid, and thiamine. There were no neurological consequences and all organ functions returned to normal, although the predicted hospital mortality based on the Sequential Organ Failure Assessment (SOFA) score was more than 90%. Conclusions: Septic shock is a significant, yet not completely understood life-threatening condition, which can be associated with purpura fulminans, multiple organ dysfunction, disseminated intravascular coagulation, and massive tissue necrosis. The Korean Society of Anesthesiologists, 2021.
Disseminated intravascular coagulation , Hypercoagulability , Purpura fulmi-nans , Sepsis , Septic shock , Therapeutic use , Vasoconstrictor agents
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Department of Biomedical Sciences, Nazarbayev University School of Medicine, Kazakhstan
Department of Anesthesiology and Critical Care, National Research Oncology Center, Kazakhstan
Department of Anesthesiology, Astana Medical University, Nur-sultan, Kazakhstan
Department of Anesthesiology and Intensive Care Medicine, Northern State Medical University, Arkhangelsk, Russian Federation
Department of Biomedical Sciences
Department of Anesthesiology and Critical Care
Department of Anesthesiology
Department of Anesthesiology and Intensive Care Medicine
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