Carbon dots-mediated fluorescent scaffolds: Recent trends in image-guided tissue engineering applications
Vedhanayagam M. Raja I.S. Molkenova A. Atabaev T.Sh. Sreeram K.J. Han D.-W.
2 May 2021MDPI
International Journal of Molecular Sciences
2021#22Issue 10
Regeneration of damaged tissues or organs is one of the significant challenges in tissue engineering and regenerative medicine. Many researchers have fabricated various scaffolds to accelerate the tissue regeneration process. However, most of the scaffolds are limited in clinical trials due to scaffold inconsistency, non-biodegradability, and lack of non-invasive techniques to monitor tissue regeneration after implantation. Recently, carbon dots (CDs) mediated fluorescent scaffolds are widely explored for the application of image-guided tissue engineering due to their controlled architecture, light-emitting ability, higher chemical and photostability, excellent biocompatibility, and biodegradability. In this review, we provide an overview of the recent advancement of CDs in terms of their different synthesis methods, tunable physicochemical, mechanical, and optical properties, and their application in tissue engineering. Finally, this review concludes the further research directions that can be explored to apply CDs in tissue engineering.
Biodegradation , Carbon dots , Fluorescent scaffold , Image-guided tissue engineering , Mechanical strength
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CATERS Laboratory, CSIR-Central Leather Research Institute, Adyar, Chennai, 600020, India
BIO-IT Fusion Technology Research Institute, Pusan National University, Busan, 46241, South Korea
Department of Chemistry, Nazarbayev University, Nur-Sultan, 010000, Kazakhstan
Department of Cogno-Mechatronics Engineering, College of Nanoscience & Nanotechnology, Pusan National University, Busan, 46241, South Korea
CATERS Laboratory
BIO-IT Fusion Technology Research Institute
Department of Chemistry
Department of Cogno-Mechatronics Engineering
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