Course and outcomes of pregnancy after minimally invasive methods for treating early-stage cervical cancer
Ukibassova T.M. Bapayeva G.B. Kamzayeva N.K. Kim Y.O. Primbetov B.U. Imankulova B.Zh.
30 September 2025Kaz Med Print LLP
Reproductive Medicine (Central Asia)
2025#2025Issue 3
Relevance: Currently, cervical cancer is a pressing problem, especially in Kazakhstan. Moreover, cervical cancer is getting younger, affecting women of fertile age. Therefore, the analysis of data on the preservation of fertility and the course and outcomes of pregnancy after treatment of cervical cancer is highly relevant. Despite the proven relationship between the human papillomavirus and the occurrence of cervical cancer and the preventive and screening measures used, cervical cancer is the 2nd most common malignant disease among women under 45 in Kazakhstan. Cervical cancer detected in reproductive age and the subsequent need for organ-removing operations leads to disability in young women, depriving them of the opportunity to have offspring. The study aimed to expand our understanding of the course and outcomes of pregnancy after minimally invasive methods of treating cervical cancer based on a review of modern literature. Materials and Methods: A literature search was conducted on female infertility, fertility preservation, and cervical cancer using available databases. Articles were searched in Scopus, PubMed, Google Scholar, and Embase databases from 2014 to mid-2024. Results: Early diagnosis of cervical cancer makes it possible to perform organ-preserving operations and preserve fertility. The observations available in the literature on reproductive outcomes are based on the results obtained in patients with early stages of cervical cancer (IB1). Conclusion: Limited data on the pregnancy course and outcomes are available from studies of patients with stage IB2 and IIA1 cervical cancer. Further research in this area and reporting on fertility-preserving treatments for stage IB2 and IIA1 cervical cancer will improve outcomes for patients.
Cervical cancer , Fertility , Pregnancy and cervical cancer , pregnancy outcomes , Reproductive function
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Department of Women’s Health, Corporate Fund “University Medical Center,”, Astana, Kazakhstan
Clinical Academic Department of Women’s Health, Corporate Fund “University Medical Center,”, Astana, Kazakhstan
Department of Women’s Health
Clinical Academic Department of Women’s Health
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