Pregnancy outcomes in women after arterial switch operation for transposition of the great arteries: Results from ropac (registry of pregnancy and cardiac disease) of the european society of cardiology eurobservational research programme
Tutarel O. Ramlakhan K.P. Baris L. Subirana M.T. Bouchardy J. Nemes A. Vejlstrup N.G. Osipova O.A. Johnson M.R. Hall R. Roos-Hesselink J.W. Aquieri A. Saad A. Vega H.R. Hojman J. Caparros J.M. Blanco M.V. Arstall M. Chung C.M. Mahadavan G. Aldridge E. Wittwer M. Chow Y.Y. Parsonage W.A. Lust K. Collins N. Warner G. Hatton R. Gordon A. Nyman E. Stein J. Donhauser E. Gabriel H. Bahshaliyev A. Guliyev F. Hasanova I. Jahangirov T. Gasimov Z. Salim A. Ahmed C.M. Begum F. Hoque M.H. Mahmood M. Islam M.N. Haque P.P. Banerjee S.K. Parveen T. Morissens M. De Backer J. Demulier L. De Hosson M. Budts W. Beckx M. Kozic M. Lovric M. Kovacevic-Preradovic T. Chilingirova N. Kratunkov P. Wahab N. McLean S. Gordon E. Walter L. Marelli A. Montesclaros A.R. Monsalve G. Rodriguez C. Balthazar F. Quintero V. Palacio W. Cadavid L.A.M. Ortiz E.M. Hoyos F.F. Guerrero E.A. Ricardo J.G. Penagos J.V. Vavera Z. Popelova J. Grønbeck L. Johansen M. Ersboll A. Elrakshy Y. Eltamawy K. Abd-El Aziz M.G. El Nagar A. Ebaid H. Elenin H.A. Saed M. Farag S. Makled W. Sorour K. Ashour Z. El-Sayed G. Mahdy M.A.A. Taha N. Dardeer A. Shabaan M. Ali M. Moceri P. Duthoit G. Gouton M. Nizard J. Cohen S. Ladouceur M. Khimoud D. Iung B. Berger F. Olsson A. Gembruch U. Merz W.M. Reinert E. Clade S. Kliesch Y. Wald C. Sinning C. Kozlik-Feldmann R. Blankenberg S. Zengin-Sahm E. Mueller G. Hillebrand M. Hauck P. Von Kodolitsch Y. Zarniko N. Baumgartner H. Schmidt R. Hellige A. Kaemmerer H. Kuschel B. Nagdyman N. Motz R. Maisuradze D. Frogoudaki A. Iliodromitis E. Anastasiou-Nana M. Triantafyllis D. Bekiaris G. Karvounis H. Giannakoulas G. Ntiloudi D. Mouratoglou S.A. Temesvari A. Balint H. Kohalmi D. Merkely B. Liptai C. Forster T. Kalapos A. Berek K. Havasi K. Ambrus N. Shelke A. Kawade R. Patil S. Martanto E. Aprami T.M. Purnomowati A. Cool C.J. Hasan M. Akbar R. Hidayat S. Dewi T.I. Permadi W. Soedarsono D.A. Ansari-Ramandi M.M. Samiei N. Tabib A. Kashfi F. Ansari-Ramandi S. Rezaei S. Ali Farhan H. Al-Hussein A. Al-Saedi G. Mahmood G. Yaseen I.F. Al-Yousuf L. AlBayati M. Mahmood S. Raheem S. AlHaidari T. Dakhil Z. Thornton P. Donnelly J. Bowen M. Blatt A. Elbaz-Greener G. Shotan A. Yalonetsky S. Goland S. Biener M. Assenza G.E. Bonvicini M. Donti A. Bulgarelli A. Prandstraller D. Romeo C. Crepaz R. Sciatti E. Metra M. Orabona R. Ait Ali L. Festa P. Fesslova V. Bonanomi C. Calcagnino M. Lombardi F. Colli A.M. Ossola M.W. Gobbi C. Gherbesi E. Tondi L. Schiavone M. Squillace M. Carmina M.G. Maina A. Macchi C. Gollo E. Comoglio F.M. Montali N. Re P. Bordese R. Todros T. Donvito V. Marra W.G. Sinagra G. D’Agata Mottolese B. Bobbo M. Gesuete V. Rakar S. Ramani F. Niwa K. Mekebekova D. Mussagaliyeva A. Lee T. Mirrakhimov E. Abilova S. Bektasheva E. Neronova K. Lunegova O. Žaliūnas R. Jonkaitienė R. Petrauskaitė J. Laucevicius A. Jancauskaite D. Lauciuviene L. Gumbiene L. Lankutiene L. Glaveckaite S. Laukyte M. Solovjova S. Rudiene V. Chee K.H. Yim C.C.-W. Ang H.L. Kuppusamy R. Watson T. Caruana M. Estensen M.-E. Kayani M.G.A.M. Munir R. Tomaszuk-Kazberuk A. Sobkowicz B. Przepiesc J. Lesniak-Sobelga A. Tomkiewicz-Pajak L. Komar M. Olszowska M. Podolec P. Wisniowska-Smialek S. Lelonek M. Faflik U. Cichocka-Radwan A. Plaskota K. Trojnarska O. Guerra N. De Sousa L. Cruz C. Ribeiro V. Jovanova S. Petrescu V. Jurcut R. Ginghina C. Coman I.M. Musteata M. Golivets T. Khamnagadaev I. Golovchenko O. Nagibina A. Ropatko I. Gaisin I.R. Shilina L.V. Sharashkina N. Shlyakhto E. Irtyuga O. Moiseeva O. Karelkina E. Zazerskaya I. Kozlenok A. Sukhova I. Jovovic L. Prokšelj K. Koželj M. Askar A.O. Abdilaahi A.A. Mohamed M.H. Dirir A.M. Sliwa K. Manga P. Pijuan-Domenech A. Galian-Gay L. Tornos P. Murga N. Oliver J.M. Garcia-Aranda Dominguez B. Gonzalez I.H. Jimenez J.F.D. Subias P.E. Elbushi A. Suliman A. Jazzar K. Murtada M. Ahamed N. Dellborg M. Furenas E. Jinesjo M. Skoglund K. Eriksson P. Gilljam T. Thilen U. Tobler D. Wustmann K. Schwitz F. Schwerzmann M. Rutz T. Greutmann M. Lopes B.M.S. Meier L. Arrigo M. De Boer K. Konings T. Wajon E. Wagenaar L.J. Polak P. Pieper E.P.G. Van Hagen I. Duvekot H. Cornette J.M.J. De Groot C. Van Oppen C. Sarac L. Esen O.B. Enar S.C. Mondo C. Ingabire P. Nalwanga B. Semu T. Salih B.T. Almahmeed W.A.R. Wani S. Farook F.S.M. Gerges F. Komaranchath A.M. Al bakshi F. Al Mulla A. Yusufali A.H. Al Hatou E.I. Bazargani N. Hussain F. Hudsmith L. Thompson P. Thorne S. Bowater S. Money-Kyrle A. Clifford P. Ramrakha P. Firoozan S. Chaplin J. Bowers N. Adamson D. Schroeder F. Wendler R. Hammond S. Nihoyannopoulos P. Freeman L. Veldtman G. Kerr J. Tellett L. Scott N. Bhatt A.B. DeFaria Yeh D. Youniss M.A. Wood M. Sarma A.A. Tsiaras S. Stefanescu A. Duran J.M. Stone L. Majdalany D.S. Chapa J. Chintala K. Gupta P. Botti J. Ting J. Davidson W.R. Wells G. Sparks D. Paruchuri V. Marzo K. Patel D. Wagner W. Ahanya S.N. Colicchia L. Jentink T. Han K. Loichinger M. Parker M. Longtin C. Yetman A. Erickson K. Cramer J. Tsai S. Fletcher B. Warta S. Cohen C. Lindblade C. Puntel R. Nagaran K. Croft N. Gurvitz M. Otto C. Talluto C. Murphy D. Perlroth M.G.
2021American Heart Association Inc.
Journal of the American Heart Association
2021#10Issue 11 - 11 pp.
BACKGROUND: In the past 3 decades, the arterial switch procedure has replaced the atrial switch procedure as treatment of choice for transposition of the great arteries. Although survival is superior after the arterial switch procedure, data on pregnancy outcomes are scarce and transposition of the great arteries after arterial switch is not yet included in the modified World Health Organization classification of maternal cardiovascular risk. METHODS AND RESULTS: The ROPAC (Registry of Pregnancy and Cardiac disease) is an international prospective registry of pregnant women with cardiac disease, part of the European Society of Cardiology EURObservational Research Programme. Pregnancy outcomes in all women after an arterial switch procedure for transposition of the great arteries are described. The primary end point was a major adverse cardiovascular event, defined as combined end point of maternal death, supraventricular or ventricular arrhythmias requiring treatment, heart failure, aortic dissection, endocarditis, ischemic coronary events, and thromboembolic events. Altogether, 41 pregnant women (mean age, 26.7±3.9 years) were included, and there was no maternal mortality. A major adverse cardiovascular event occurred in 2 women (4.9%): heart failure in one (2.4%) and ventricular tachycardia in another (2.4%). One woman experienced fetal loss, whereas no neonatal mortality was observed. CONCLUSIONS: Women after an arterial switch procedure for transposition of the great arteries tolerate pregnancy well, with a favorable maternal and fetal outcome. During counseling, most women should be reassured that the risk of pregnancy is low. Classification as modified World Health Organization risk class II seems appropriate.
Arterial switch operation , Pregnancy and cardiac disease , Pregnancy outcomes , Transposition of the great arteries
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Department of Congenital Heart Disease and Paediatric Cardiology, German Heart Centre Munich, Technical University of Munich School of Medicine, Technical University of Munich, Germany
DZHK (German Centre for Cardiovascular Research), Partner site Munich Heart Alliance, Munich, Germany
Department of Cardiology, Erasmus University Medical Center, Rotterdam, Netherlands
Adult Congenital Heart Disease Unit Vall d’Hebrón-Sant Pau, Barcelona, Spain
Service of Cardiology, University Hospital Lausanne, University of Lausanne, Switzerland
Service of Cardiology, University of Geneva, Switzerland
2nd Department of Medicine and Cardiology Centre, Medical Faculty, Albert Szent-Györgyi Clinical Center, University of Szeged, Hungary
Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
Department of Pregnancy Pathology, Perinatal Centre of Belgorod Regional Clinical Hospital of St Iosaph, Belgorod, Russian Federation
Belgorod State University, Belgorod, Russian Federation
Department of Obstetric Medicine, Imperial College London, Chelsea and Westminster Hospital, London, United Kingdom
Department of Cardiology, University of East Anglia, Norwich, United Kingdom
Buenos Aires, Argentina
Elizabeth Vale, Australia
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Department of Congenital Heart Disease and Paediatric Cardiology
DZHK (German Centre for Cardiovascular Research)
Department of Cardiology
Adult Congenital Heart Disease Unit Vall d’Hebrón-Sant Pau
Service of Cardiology
Service of Cardiology
2nd Department of Medicine and Cardiology Centre
Department of Cardiology
Department of Pregnancy Pathology
Belgorod State University
Department of Obstetric Medicine
Department of Cardiology
Buenos Aires
Elizabeth Vale
Herston
New Lambton Heights
Innsbruck
Vienna
Baku
Dhaka
Brussels
Gent
Leuven
Banja Luka
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