Modern aspects of chronic cerebral ischemia pathogenetic therapy
Turuspekova S.T. Nurguzhaev E.S. Nurzhanova R.B. Demesinova B.C. Karimov G.K. Dyusembaeva Z.B. Mamashayev N.K. Myrzamuratova D.
2024Media Sphera Publishing Group
Zhurnal Nevrologii i Psihiatrii imeni S.S. Korsakova
2024#124Issue 12106 - 113 pp.
Chronic cerebral ischemia (CCI) is one of the most common forms of cerebrovascular disease, which affects a significant number of patients, often leading to disability, cognitive impairment and dementia. The analysis of modern data on the pathogenesis and risk factors for the development of CCI, as well as on the mechanisms of action of Mexidol on various links in the pathogenesis of CCI. A systematic search was conducted in the PubMed, MEDLINE and Google Scholar databases, on Russian and English-language sites with open access publications on the problem of CCI and on the drug Mexidol in the period from 2014 to 2024. The analysis included randomized controlled trials, meta-analyses and original studies, excluded low-confidence studies, retrospective studies, literature reviews, systematic reports and descriptions of clinical cases. It has been established that the use of Mexidol leads to a significant regression of cognitive, emotional, autonomic and motor disorders in CCI. An important indicator of the effectiveness of Mexidol is the high degree of patient adherence to therapy. It is recommended to start treatment with injection of Mexidol, followed by a transition to tablet forms.
arterial hypertension , cerebrovascular diseases , chronic cerebral ischemia , cognitive impairment , Mexidol , neurology , neuroprotection
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S.D. Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
City Clinical Hospital No. 7, Almaty, Kazakhstan
S.D. Asfendiyarov Kazakh National Medical University
City Clinical Hospital No. 7
10 лет помогаем публиковать статьи Международный издатель
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