SYNTHESIS AND CRYSTAL STRUCTURE OF N-ETHYL-N-CYTISINOCARBOTHIOAMIDE
Turdybekov K.M. Nurkenov O.A. Turdybekov D.M. Satpaeva Z.B. Fazylov S.D.
November 2021Pleiades journals
Journal of Structural Chemistry
2021#62Issue 111678 - 1683 pp.
Abstract: Based on (–)-cytisine alkaloid and ethyl isothiocyanate, N-ethyl-N-cytisinocarbothioamide is synthesized and its structure is proved by 1H NMR spectroscopy and single crystal X-ray diffraction. The mesomeric effect is shown in the carbothioamide group formed. It is found that π-conjugation between nitrogen atoms and the thiocarbonyl group is weakened due to the steric hindrance between hydrogen atoms of the piperidine ring and the thioamide group. [Figure not available: see fulltext.]
alkaloids , carbothioamide , cytisine , ethyl isothiocyanate , NMR spectroscopy , single crystal X-ray diffraction
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Buketov Karaganda State University, Karaganda, Kazakhstan
Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan, Karaganda, Kazakhstan
Karaganda State Technical University, Karaganda, Kazakhstan
Buketov Karaganda State University
Institute of Organic Synthesis and Coal Chemistry of the Republic of Kazakhstan
Karaganda State Technical University
10 лет помогаем публиковать статьи Международный издатель
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