Molecular Structure and Absolute Configuration of Tatridin A and B from Lepidolopha karatavica


Turdybekov K.M. Morozova O.A. Ivasenko S.A. Makhmutova A.S. Turdybekov D.M. Adekenov S.M.
January 2021Springer

Chemistry of Natural Compounds
2021#57Issue 183 - 87 pp.

The germacrane-type sesquiterpene lactones tatridin A and B were isolated for the first time during chemical studies of the extract of Lepidolopha karatavica. The structures of the compounds were elucidated using spectral data and X-ray crystal structure analyses (XSAs). Correlations of the XSAs and CD spectra defined the absolute configurations of the molecules. Possible conformational states of 3,8-deoxytatridin A and B were calculated by a quantum chemical method.

crystal structure , Lepidolopha karatavica , molecular conformation , NMR , sesquiterpene lactones , XSA

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E. A. Buketov Karaganda State University, 28 Universitetskaya St, Karaganda, 100028, Kazakhstan
International Scientific-Production Holding Phytochemistry, 4 Gazalieva St, Karaganda, 100009, Kazakhstan
Medical University of Karaganda, 40 Gogolya St., Karaganda, 100000, Kazakhstan
Karaganda State Technical University, 56 Prosp. N. Nazarbaeva, Karaganda, 100000, Kazakhstan

E. A. Buketov Karaganda State University
International Scientific-Production Holding Phytochemistry
Medical University of Karaganda
Karaganda State Technical University

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