Clinical Features and Pathogenesis of Atrophic Rhinitis in a Sharp Continental Climate: A Literature Review
Tulebaev R. Kapysheva A. Makhambetova E. Azhenov T.
2024Professionalnye Izdaniya
Otorhinolaryngology Eastern Europe
2024#14Issue 1101 - 108 pp.
Introduction. Among chronic rhinitis, vasomotor and atrophic rhinitis occupy a significant share. Currently, vasomotor rhinitis, from the point of view of the nature of its origin and some mechanisms of its occurrence, is considered the most studied. As for atrophic rhinitis, a number of etiological factors and the pathogenesis of this disease from the point of view of the underlying causes, its relationship with the pathology of disorders of the mucous membranes of the upper respiratory tract and the whole organism as a whole, have not yet been sufficiently studied. Many researchers believe that atrophic rhinitis is a chronic disease of the nasal mucosa, characterized by atrophic changes in the nasal septum and turbinates and affects its structural components, including homeostasis, as well as the glands that produce mucous secretion, which determines the basic physiological functions of this epithelium. Purpose. To study the clinical features and pathogenesis of atrophic rhinitis. Materials and methods. The analysis of sources of Kazakh and foreign literature was carried out using scientific literature databases for the period from 1979 to 2023. Results. After analyzing the available literature, we came to the conclusion that despite numerous assumptions about the causes of the development of atrophic rhinitis, the etiology and pathogenesis of this disease are not fully understood. Conclusion. Unfortunately, to this day the place of atrophic rhinitis in the general classification of diseases has not been determined; there is no clear diagnostic algorithm, effective treatment methods and preventive measures for the disease in Kazakhstan as a whole. This pathology deserves special attention due to the fact that it affects the nasal mucosa to its deep layers, is characterized by a progressive course and still has no effective treatment.
atrophic rhinitis , granulomatosis , homeostasis , mucociliary clearance , nasal septum
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Astana Medical University, Astana, Kazakhstan
ENT Center Sezim, Astana, Kazakhstan
Astana Medical University
ENT Center Sezim
10 лет помогаем публиковать статьи Международный издатель
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