How does RIRS impact on stent-related symptoms? Insights from a prospective observational study by EAU-YAU endourology and urolithiasis working group
Tsaturyan A. Keller E.X. Mancon S. Grigoryan H. Sener T.E. Ventimiglia E. Esperto F. De Coninck V. Juliebø-Jones P. Ballesta Martinez B. Mykoniatis I. Del Rio A.S. Tzelves L. Olivero A. Corrales M. Jahrreiss V. Talyshinskii A. Boeykens M. Ergul R. Nowak L. Pietropaolo A.
December 2025Springer Science and Business Media Deutschland GmbH
World Journal of Urology
2025#43Issue 1
Purpose: To assess the perception and severity of stent-related symptoms (SRS) in patients undergoing retrograde intrarenal surgery (RIRS). Materials and methods: A prospective observational study was performed including patients with single or multiple renal stones undergoing ureteral stenting and scheduled for a definitive RIRS. SRS were evaluated at 3 timepoints: pre-operatively on the day of RIRS, as well as on the 1st and 7th postoperative day following RIRS. Bladder pain, back pain, hematuria, urgency, frequency, nocturia, and urge incontinence were evaluated using a visual analog scoring (VAS) system. Results: A total of 57 patients were included. The patients reported a significant rise in back pain at day 1 after RIRS (mean rank 2.25 on a scale of 0 to 5) compared to preoperative scores (2.06), with a significant decrease at day 7 following RIRS (1.68) (p = 0.003). A similar pattern was observed for bladder pain, frequency and urge incontinence (all p < 0.001). As for urgency and nocturia, these SRS steadily decreased from baseline to day 1, and in turn from day 1 to day 7 after RIRS (p = 0.004 and p = 0.003, respectively). Hematuria was the only SRS which did not show any significant differences over the 3 evaluated timepoints. Conclusion: RIRS temporarily increases certain SRS, particularly pain and urinary discomfort within the first 24 h postoperatively. These symptoms tend to improve by the 7th postoperative day, suggesting that surgery itself may contribute to the early symptom burden but ultimately facilitates recovery. Further multi-center prospective studies with bigger sample size are warranted to confirm our findings.
Lithotripsy , RIRS , Stent-related symptoms , Ureteral stenting , Ureteroscopy
Text of the article Перейти на текст статьи
Department of Urology, Yerevan State Medical University, Yerevan, Armenia
Department of Urology, Erebouni Medical Center, Yerevan, 0087, Armenia
EAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group Arnhem, Arnhem, NL-6803, Netherlands
Department of Urology, University Hospital Zurich, University of Zurich, Zurich, Switzerland
Department of Urology, Humanitas Clinical and Research Institute IRCCS, Rozzano, Milan, Italy
Department of Urology, Marmara University School of Medicine, Istanbul, 34854, Turkey
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
Department of Urology, Campus Biomedico University of Rome, Rome, 00128, Italy
Department of Urology, AZ Klina, Brasschaat, Antwerp, 2930, Belgium
Department of Urology, Haukeland University Hospital, Bergen, N-5021, Norway
Department of Urology, University Hospital del Vinalopo, Alicante, Spain
Department of Urology, Aristotle University of Thessaloniki, Thessaloniki, Greece
Department of Urology, Hospital Clinic de Barcelona, Barcelona, Spain
2nd Department of Urology, Sismanoglio General Hospital, National and Kapodistrian University of Athens (NKUA), Marousi, Greece
Department of Urology, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy
Sorbonne University GRC Urolithiasis No. 20 Tenon Hospital, Paris, 75020, France
Department of Urology, Medical University of Vienna, Vienna, Austria
Department of Urology and Andrology, Astana Medical University, Astana, Kazakhstan
Department of Urology, University Hospital Ghent, Oost- Vlaanderen, Ghent, 9000, Belgium
Department of Urology, AZ Delta Roeselare, Deltalaan 1, Roeselare, 8800, Belgium
Department of Urology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
Department of Minimally Invasive and Robotic Urology, University Centre of Excellence in Urology, Wroclaw Medical University, Wroclaw, Poland
Department of Urology, University Hospital Southampton NHS Foundation Trust, Southampton, SO16 6YD, United Kingdom
Department of Urology
Department of Urology
EAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group Arnhem
Department of Urology
Department of Urology
Department of Urology
Department of Surgical Sciences
Department of Urology
Department of Urology
Department of Urology
Department of Urology
Department of Urology
Department of Urology
2nd Department of Urology
Department of Urology
Sorbonne University GRC Urolithiasis No. 20 Tenon Hospital
Department of Urology
Department of Urology and Andrology
Department of Urology
Department of Urology
Department of Urology
Department of Minimally Invasive and Robotic Urology
Department of Urology
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026