Minimalistic design and rapid-fabrication single-mode fiber biosensors: Review and perspectives
Tosi D. Shaimerdenova M. Sypabekova M. Ayupova T.
September 2022Academic Press Inc.
Optical Fiber Technology
2022#72
Optical fiber biosensors are receiving significant interest, as they allow real-time, low-limit, and high precision detection of biological analytes such as biomarkers, proteins, and small cells. Classical biosensor designs include gratings, interferometers, and plasmonic structures; however, these systems require a complex design, hard to manufacture on high volumes. Recently, several biosensors having a minimalistic design, rapid and suitable to be automated, have been proposed; the key asset is the scalability potential, in view of fabricating numerous devices for disposable use or for large parallel immunoassays. This new sensor class features reflector-less sensors, shallow tapers, and ball resonators; a pseudo-random spectrum characterizes all these biosensors. In this paper, we provide a bird-eye view of these minimalistic designs and a perspective of their use in advanced biosensing applications.
Ball resonator , Fiber taper , Optical fiber biosensors , Random spectra , Rayleigh scattering , Reflector-less sensors , Refractive index sensor , The ultralow limit of detection
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Nazarbayev University, School of Engineering and Digital Sciences, 53 Kabanbay Batyr, Nur-Sultan, 010000, Kazakhstan
National Laboratory Astana, Laboratory of Biosensors and Bioinstruments, 53 Kabanbay Batyr, Nur-Sultan, 010000, Kazakhstan
Baylor University, Department of Electrical and Computer Engineering, Waco, TX, United States
Nazarbayev University
National Laboratory Astana
Baylor University
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