Investigation of CO2Extract of Portulaca oleracea for Antioxidant Activity from Raw Material Cultivated in Kazakhstan
Tleubayeva M.I. Abdullabekova R.M. Datkhayev U. Ishmuratova M.Y. Alimzhanova M.B. Kozhanova K.K. Seitaliyeva A.M. Zhakipbekov K.S. Iskakova Z.B. Serikbayeva E.A. Flisyuk E.V.
2022Hindawi Limited
International Journal of Biomaterials
2022#2022
Medicinal plants remain as an important resource in the fight against many diseases, especially in developing countries. Antioxidants are substances capable of delaying, retarding, and preventing the oxidation of lipids or substances that delay or prevent free radical reactions during lipid oxidation. Natural antioxidants such as ascorbic acid, tocopherol, phenolic compounds, and flavonoids are a safe alternative to chemical antioxidants. In present work, results of antioxidant activity of raw materials from the cultivated plant Portulaca oleracea are presented. The extraction time was optimized to 780 minutes; the yield of extractive substances was 1.25% in the production of CO2 extract under subcritical conditions. For the first time, the antioxidant activity of Portulaca oleracea CO2 extract was determined by the amperometric method. Gas chromatography-mass spectrometry (GC-MS) chemical analysis of Portulaca oleracea CO2 extract dissolved in hexane revealed 37 components, including a complex mixture of aldehydes, alkanes, alkenes, esters, diterpenes, steroids, vitamin E, and carbohydrates. The investigation results showed that the Portulaca oleracea CO2 extract was promising for pharmaceutical, cosmetic, and food industries and had great potential for the prevention and treatment of diseases caused by oxidative stress.
Text of the article Перейти на текст статьи
Department Of Organization And Management And Economics Of Pharmacy And Clinical Pharmacy, Department Of Engineering Disciplines, School Of Pharmacy, Njsc Karaganda Medical University, Karaganda Medical University, Tole Bi 88 Str, Almaty, 050000, Kazakhstan
Departament Of Pharmaceutical Disciplines And Chemistry, Njsc Karaganda Medical University, Gogol 40 Str, Karaganda, 100008, Kazakhstan
Department Of Botany, Karaganda Buketov University, Universitetskaya 28 Str, Karaganda, 100024, Kazakhstan
Department Of Thermal Physics And Technical Physics, Faculty Of Physics And Technology, Al-Farabi Kazakh National University, Al-Farabi Ave 71, Almaty, 050040, Kazakhstan
Department Of Fundamental Medicine, Faculty Of Medicine And Health, Al-Farabi Kazakh National University, Al-Farabi Ave 71, Almaty, 050040, Kazakhstan
Research Institute Of New Chemical Technologies, L.N. Gumilyov Eurasian National University, Satpaev 2 Str, Nur-Sultan, 010000, Kazakhstan
Departament Of Technology Of Drugs Forms, St. Petersburg State Chemical And Pharmaceutical University, Popov 14 Str, Petersburg, 197376, Russian Federation
Department Of Organization And Management And Economics Of Pharmacy And Clinical Pharmacy
Departament Of Pharmaceutical Disciplines And Chemistry
Department Of Botany
Department Of Thermal Physics And Technical Physics
Department Of Fundamental Medicine
Research Institute Of New Chemical Technologies
Departament Of Technology Of Drugs Forms
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026