Pipelle endometrial sampling success rates in Kazakhstani settings: results from a prospective cohort analysis
Terzic M. Aimagambetova G. Bapayeva G. Ukybassova T. Kenbayeva K. Kaiyrlykyzy A. Ibrayimov B. Lyasova A. Terzic S. Alkatout I. Gitas G. Hortu İ. Garzon S. Laganà A.S.
2022Taylor and Francis Ltd.
Journal of Obstetrics and Gynaecology
2022#42Issue 51255 - 1260 pp.
The aim of this study was to evaluate the feasibility of Pipelle endometrial sampling and to explore factors influencing Pipelle success rate in the clinical settings of Kazakhstan. This prospective analysis included 87 patients who had undergone Pipelle biopsy due to medical indications for endometrial sampling. We analysed physician and patient-related factors potentially influencing the success rate of this method. Pipelle endometrial biopsy overall success rate was 82.76%. The indications for the procedure and patients’ age were key factors influencing Pipelle sampling success (p <.001). The success rate was the highest in the group with abnormal uterine bleeding as a biopsy indication in the reproductive age group (93.19%; p <.001). Pipelle biopsy was found to be an acceptable option for endometrial sampling in our clinical setting; at the same time, physicians should consider the potential influencing factors on its success rate like indications for the procedure, BMI and patients’ age as well as their menopausal status. In order to provide precise future directions, there is a need to study a larger number of patients.IMPACT STATEMENTWhat is already known on this subject? Compared to dilation and curettage sampling conducted in the operation room, Pipelle endometrial sampling is relatively inexpensive, associated with less morbidity, safe, accurate, and can be performed in an office setting. What do the results of this study add? This is the first prospective data analysis about Pipelle endometrial sampling in Kazakhstani population. What are the implications of these findings for clinical practice and/or further research? Enabling the timely diagnosis of current endometrial pathology, Pipelle endometrial sampling approach may have an important impact on healthcare safety and efficiency, and improve overall treatment outcomes and the quality of life of Kazakhstani population if used consistently.
Abnormal uterine bleeding , dilatation and curettage , endometrial hyperplasia , endometrial sampling , Pipelle biopsy
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Department of Medicine, School of Medicine, Nazarbayev University, Nur-Sultan, Kazakhstan
Clinical Academic Department of Women’s Health, National Research Center of Mother and Child Health, University Medical Center, Nur-Sultan, Kazakhstan
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
Department of Biomedical Sciences, School of Medicine, Nazarbayev University, Nur-Sultan, Kazakhstan
National Laboratory of Astana, Nazarbayev University, Nur-Sultan, Kazakhstan
Department of Pathological Anatomy, National Research Center of Mother and Child Health, University Medical Center, Nur-Sultan, Kazakhstan
Pathology Bureau of Nur-Sultan City Administration, Nur-Sultan, Kazakhstan
Department of Obstetrics and Gynecology, University Hospital Schleswig Holstein, Kiel, Germany
Department of Obstetrics and Gynecology, University Hospital Schleswig Holstein, Lübeck, Germany
Department of Obstetrics and Gynaecology, Faculty of Medicine, Ege University, İzmir, Turkey
Department of Stem Cell, Institute of Health Sciences, Ege University, İzmir, Turkey
lDepartment of Obstetrics and Gynecology, AOUI Verona, University of Verona, Verona, Italy
Department of Obstetrics and Gynecology, “Filippo Del Ponte” Hospital, University of Insubria, Varese, Italy
Department of Medicine
Clinical Academic Department of Women’s Health
Department of Obstetrics
Department of Biomedical Sciences
National Laboratory of Astana
Department of Pathological Anatomy
Pathology Bureau of Nur-Sultan City Administration
Department of Obstetrics and Gynecology
Department of Obstetrics and Gynecology
Department of Obstetrics and Gynaecology
Department of Stem Cell
lDepartment of Obstetrics and Gynecology
Department of Obstetrics and Gynecology
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