Molecular basis of endometriosis and endometrial cancer: Current knowledge and future perspectives
Terzic M. Aimagambetova G. Kunz J. Bapayeva G. Aitbayeva B. Terzic S. Laganà A.S.
1 September 2021MDPI
International Journal of Molecular Sciences
2021#22Issue 17
The human endometrium is a unique tissue undergoing important changes through the menstrual cycle. Under the exposure of different risk factors in a woman’s lifetime, normal endo-metrial tissue can give rise to multiple pathologic conditions, including endometriosis and endo-metrial cancer. Etiology and pathophysiologic changes behind such conditions remain largely un-clear. This review summarizes the current knowledge of the pathophysiology of endometriosis and its potential role in the development of endometrial cancer from a molecular perspective. A better understanding of the molecular basis of endometriosis and its role in the development of endome-trial pathology will improve the approach to clinical management.
Endometrial cancer , Endometriosis , Molecular basis of endometriosis , Ovarian cancer
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Department of Medicine, School of Medicine, Nazarbayev University, Kabanbay Batyr Avenue 53, Nur-Sultan, 010000, Kazakhstan
National Research Center for Maternal and Child Health, Clinical Academic Department of Women’s Health, University Medical Center, Turan Avenue 32, Nur-Sultan, 010000, Kazakhstan
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, School of Medicine, 300 Halket Street, Pittsburgh, 15213, PA, United States
Department of Biomedical Sciences, School of Medicine, Nazarbayev University, Kabanbay Batyr Avenue 53, Nur-Sultan, 010000, Kazakhstan
Department of Obstetrics and Gynecology, “Filippo Del Ponte” Hospital, University of Insubria, Varese, 21100, Italy
Department of Medicine
National Research Center for Maternal and Child Health
Department of Obstetrics
Department of Biomedical Sciences
Department of Obstetrics and Gynecology
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