CT-based radiomics for predicting stone-free rate after ESWL: a systematic review and meta-analysis
Talyshinskii A. Ali S. Gauhar V. Güven S. Somani B.K. Sarica K. Gadzhiev N.
December 2025Springer Science and Business Media Deutschland GmbH
World Journal of Urology
2025#43Issue 1
Purpose: To evaluate the prognostic significance of computed tomography (CT)-based radiomic features of urinary stones in predicting stone-free rate (SFR) after extracorporeal shockwave lithotripsy (ESWL) and laser lithotripsy. Methods: A systematic literature search of several databases using Boolean operators was performed according to PRISMA guideline and registered in PROSPERO (CRD420250650566). Studies using CT-based radiomics to predict SFR after ESWL or laser lithotripsy and reporting area under the receiver operating characteristic curve (AUC) with 95% confidence intervals (CI) were included. CLAIM and PROBAST checklists were used to assess transparency and and and risk of bias, respectively. A random-effects meta-analysis was performed to pool AUC estimates and assess heterogeneity. Results: Seven studies were selected and analyzed, of which five described radiomic prediction for ESWL and were analyzed in the meta-analysis. The pooled AUC for radiomics-based models predicting SFR after ESWL was 0.883 (95% CI: 0.840–0.927), with low heterogeneity (I2 = 24.3%) and a prediction interval of 0.77–0.96. All studies were rated at high risk of bias with moderate compliance. Conclusion: Adding CT-based radiomic features of stones to other clinical and radiologic parameters can predict SFR after ESWL with an AUC of > 0.85. However, the results are based on a small number of studies mostly with a high risk of bias, so follow-up studies performed according to the tenets of using radiomic analysis are needed.
CT , ESWL , Radiomics , SFR , Urolithiasis
Text of the article Перейти на текст статьи
Department of Urology, Astana Medical University, Astana, Kazakhstan
Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russian Federation
Ng Teng Fong General Hospital, Singapore, Singapore
Asian Institute of Nephro-Urology, Hyderabad, India
Department of Urology, Medical Faculty, Necmettin Erbakan University, Konya, Turkey
University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom
Department of Urology, Health Sciences University, Prof. Dr. Ilhan Varank Education and Training Hospital, Istanbul, Turkey
Department of Urology, Medical School, Biruni University, Istanbul, Turkey
Department of Urology, St. Petersburg State University Hospital, St. Petersburg, Russian Federation
Department of Urology
Institute for Urology and Reproductive Health
Ng Teng Fong General Hospital
Asian Institute of Nephro-Urology
Department of Urology
University Hospital Southampton NHS Foundation Trust
Department of Urology
Department of Urology
Department of Urology
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026