Sarcoidosis and occupational hazards: a systematic review of research in the countries of the former Soviet Union

Strizhakov L.A. Vinnikov D.V. Rybina T.M. Babanov S.A. Mukatova I.Y.U.
2022 Media Sphera Publishing Group

Profilakticheskaya Meditsina
2022 #25 Issue 2 91 - 99 pp.

The purpose of the review. To summarize the results of studies on the role of harmful factors of the working environment in the development of sarcoidosis, published in Russian and English in the Russian Federation, Belarus, Ukraine, Kazakhstan, Kyrgyzstan, Tajikistan, Uzbekistan, Turkmenistan, Georgia, Azerbaijan, Armenia, Moldova, Latvia, Lithuania and Estonia. Material and methods. Following the PRISMA protocol, we searched the databases www.elibrary.ru, IBIS, PubMed and the paper catalog of the Belarusian State Library for descriptions of all available studies performed in 15 countries from the time of the first publication in 1936 until January 2021, in which studied the relationship of harmful factors of the working environment with the development of sarcoidosis. The quality of individual studies was assessed using the ARHQ methodology checklist. Results. Only four studies published between 1996 and 2018 in Russia and Belarus, all in Russian, met the inclusion criteria and were included in the analysis. These studies, with a cross-sectional (75%) and cohort design, found a prevalence of occupational hazards in patients with sarcoidosis ranging from 8 to 61%. The quality of the included studies is very low, with a high risk of selection bias, exposure classification and disease verification errors, and confounding factors. Conclusions. In the countries of the former Soviet Union, research on the role of exposure to harmful factors of the working environment in the development of sarcoidosis has either not been carried out, or very little attention has been paid to them. Evidence for the role of these factors in the development of sarcoidosis collected so far is of low quality, which serves as a basis for planning more high-quality studies.

Cross-sectional study , Occupational hazards , Sarcoidosis , Systematic review

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Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russian Federation
Lomonosov Moscow State University named of the Ministry of Education and Science of Russia, Moscow, Russian Federation
Al-Farabi Kazakh National University, Alma-Ata, Kazakhstan
Peoples Friendship University of Russia of the Ministry of Education and Science of Russia, Moscow, Russian Federation
Republican Center for Labor Protection of the Ministry of Labor and Social Protection of the Republic of Belarus, Minsk, Belarus
University of Civil Protection of the Ministry of Emergency Situations of the Republic of Belarus, Minsk, Belarus
Scientific and Practical Center MedAveri, Minsk, Belarus
Samara State Medical University of the Ministry of Health of Russia, Samara, Russian Federation
Astana Medical University, Nur-Sultan, Kazakhstan

Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation
Lomonosov Moscow State University named of the Ministry of Education and Science of Russia
Al-Farabi Kazakh National University
Peoples Friendship University of Russia of the Ministry of Education and Science of Russia
Republican Center for Labor Protection of the Ministry of Labor and Social Protection of the Republic of Belarus
University of Civil Protection of the Ministry of Emergency Situations of the Republic of Belarus
Scientific and Practical Center MedAveri
Samara State Medical University of the Ministry of Health of Russia
Astana Medical University

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