Cyclic Imines and Their Salts as Universal Precursors in the Synthesis of Nitrogen-Containing Alkaloids
Smolobochkin A. Gazizov A. Sidlyaruk N. Akylbekov N. Zhapparbergenov R. Burilov A.
January 2025Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
2025#26Issue 1
Alkaloids are predominantly nitrogen-containing heterocyclic compounds that are usually isolated from plants, and sometimes from insects or animals. Alkaloids are one of the most important types of natural products due to their diverse biological activities and potential applications in modern medicine. Cyclic imines were chosen as starting compounds for the synthesis of alkaloids due to their high synthetic potential. Thus, this review summarizes the achievements in the synthesis of various alkaloids from cyclic imines, paying special attention to stereoselective methods used for their preparation. Information on the biological activity of some alkaloids, their application and occurrence in natural objects is presented. Synthesis methods are classified based on the type of alkaloid obtained.
alkaloids , cyclic imines , N-heterocycles , natural products
Text of the article Перейти на текст статьи
Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan, 420088, Russian Federation
Laboratory of Engineering Profile, Department of Engineering Technology, Korkyt Ata Kyzylorda University, Aiteke bi Str., 29A, Kyzylorda, 120014, Kazakhstan
Arbuzov Institute of Organic and Physical Chemistry
Laboratory of Engineering Profile
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026