Bioactive compounds from Prosopis species as potential oxidative stress and inflammation modulators: an update on mechanisms


Sharifi-Rad J. Elmenyiy N. Ydyrys A. Elhachlafi N. Elomari N. Aldahish A.A. Sharopov F. Bouyahya A. Živković J. Adetunji C.O. Olaniyan O.T. Martorell M. Sönmez Gürer E. Hano C. Calina D.
June 2023Edizioni Minerva Medica

Minerva Biotechnology and Biomolecular Research
2023#35Issue 2127 - 144 pp.

Oxidative stress and inflammation processes are involved in most diseases and illnesses. Many herbal remedies have been shown to have anti-inflammatory and antioxidant effects, and have been used since ancient times as traditional medicine. Species of the genus Prosopis are one of these herbal remedies that grow in arid, semiarid, subtropical, and tropical areas of the world. Paste, gum, and smoke from pods and leaves of Prosopis plants are traditionally used to treat diseases related to oxidative stress and inflammation. This review aims to provide up-to-date information on Prosopis plants as oxidative stress and inflammation modulators. Relevant information was collected from researching scientific databases such as PubMed/Medline, Wiley, Web of science and springer. Folk medicinal applications and biologically active molecules of Prosopis spp., and its derivatives, have been collected paying attention to studies that used verified markers of oxidative stress, antioxidant capacity and inflammation. Future studies are needed to deepen more pharmacodynamic, pharmacokinetic and structure-activity relationships of phytochemicals isolated from Prosopis species.

Antioxidants , Inflammation , Oxidative stress , Prosopis

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Faculty of Medicine, university of azuay, Cuenca, Ecuador
laboratory of Pharmacology, National agency of Medicinal and aromatic Plants, Taounate, Morocco
Biomedical Research Center, Al-Farabi Kazakh National University, Almaty, Kazakhstan
the elliott school of international affairs, george Washington university, Washington, DC, United States
Microbial Biotechnology and Bioactive Molecules laboratory, Faculty of sciences and technologies, sidi Mohmed Ben abdellah university, Fez, Morocco
laboratory of histology, embryology, and cytogenetic, Faculty of Medicine and Pharmacy, Mohammed V university,, rabat, Morocco
department of Pharmacology and Toxicology, College of Pharmacy, King Khalid University, Asir, Saudi Arabia
chinese-tajik innovation center for Natural Products research institution, National academy of sciences of tajikistan, dushanbe, Tajikistan
laboratory of human Pathologies, department of Biology, Faculty of sciences, genomic center of human Pathologies, Mohammed V university,, rabat, Morocco
Institute for Medicinal Plants Research “Dr Josif Pančić”, Belgrade, Serbia
applied Microbiology, Biotechnology and Nanotechnology laboratory, department of Microbiology, auchi, Nigeria
laboratory for reproductive Biology and developmental Programming, department of Physiology, edo university iyamho, auchi, Nigeria
department of Nutrition and dietetics, Faculty of Pharmacy and center for healthy living, university of concepción, concepción, Chile
unit of technological development, university of concepción, concepción, Chile
department of Pharmacognosy, Faculty of Pharmacy, sivas cumhuriyet university, sivas, Turkey
laboratory of tree and Field crop Biology (lBlgc), university of orléans, orléans, France
department of clinical Pharmacy, university of Medicine and Pharmacy, craiova, Romania
Faculty of Medicine, University of Azuay, Cuenca, Ecuador

Faculty of Medicine
laboratory of Pharmacology
Biomedical Research Center
the elliott school of international affairs
Microbial Biotechnology and Bioactive Molecules laboratory
laboratory of histology
department of Pharmacology and Toxicology
chinese-tajik innovation center for Natural Products research institution
laboratory of human Pathologies
Institute for Medicinal Plants Research “Dr Josif Pančić”
applied Microbiology
laboratory for reproductive Biology and developmental Programming
department of Nutrition and dietetics
unit of technological development
department of Pharmacognosy
laboratory of tree and Field crop Biology (lBlgc)
department of clinical Pharmacy
Faculty of Medicine

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