The Clinical Case of Successful Application of Photodynamic Therapy in the Skin Metastases Treatment of Breast Cancer
Shanazarov N. Zinchenko S. Zhapparov E. Muratov N. Turzhanova D. Bilyalov A. Tashpulatov T.
December 2021Springer
BioNanoScience
2021#11Issue 4957 - 961 pp.
The article describes the experience of using photodynamic therapy in the treatment of skin metastases of a patient with breast cancer. The authors note the high effectiveness of this method of treatment in combination with safety. The obtained data allow us to conclude that photodynamic therapy is a very promising method of treating this cohort of patients. Patient K., 69 years old, was diagnosed with cancer of the left breast in October 2015. T2N3M0. Stage IIIC. Complex treatment was carried out: 2 courses of neoadjuvant chemotherapy + radical mastoectomy + remote radiation therapy summation of the focal dose 30gr + 4 courses of adjuvant chemotherapy. In the period up to February 2020, the patient repeatedly received supportive treatment in the palliative care department. Taking into account the volume of metastatic skin lesions, palliative multi-course PDT was recommended. As a result of the treatment, a partial regression of the tumor was obtained. On examination, the scar in the area of PDT is pale pink; the continued growth of the tumor is determined in the form of separate areas of infiltration along the anterior edge of the scar.
Breast cancer , Photodynamic therapy , Skin metastases
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Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan, Nursultan, Kazakhstan
Center of Photodynamic Therapy of the Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine, Chelyabinsk, Russian Federation
Kazan Federal University, Kazan, Russian Federation
Tatarstan Cancer Center, Kazan, Russian Federation
Multidisciplinary Medical Center of the Akimat, Nursultan, Kazakhstan
NJSC “Astana Medical University,”, Nur-Sultan, Kazakhstan
Medical Centre Hospital of President’s Affairs Administration of the Republic of Kazakhstan
Center of Photodynamic Therapy of the Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine
Kazan Federal University
Tatarstan Cancer Center
Multidisciplinary Medical Center of the Akimat
NJSC “Astana Medical University
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