CLINICAL CASE OF SUCCESSFUL APPLICATION OF PHOTODYNAMIC THERAPY IN ADVANCED VULVAR CANCER


КЛИНИЧЕСКИЙ СЛУЧАЙ УСПЕШНОГО ПРИМЕНЕНИЯ ФОТОДИНАМИЧЕСКОЙ ТЕРАПИИ ПРИ РАСПРОСТРАНЕННОМ РАКЕ ВУЛЬВЫ
Shanazarov H.А. Grishachevа T.G. Aldabergen G.S. Smailova S.B. Salmaganbetova Zh.Zh.
2023Russian Photodynamic Association

Biomedical Photonics
2023#12Issue 321 - 24 pp.

A significant therapeutic effect of photodynamic therapy (PDT) is shown in a patient with extensive vulvar cancer after ineffective surgical an chemoradiotherapy. During the year, three courses of local PDT with a photosensitizer based on chlorin e6 were carried out. The photosensitize was administered intravenously three hours before irradiation at a dose of 1.2 mg/kg. For laser irradiation (662 nm) of the vulvar tumor, a ligh guide for external irradiation was used: the power density was 0.2 W/cm2, the light dose was from 100 to 250 J/cm2. As a result of treatment, tumo regression and stable remission are observed. The patient remains under observation.

clinical case , local photodynamic therapy , photolon , vulvar cancer

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Medical Center Hospital of the President’s Affairs Administration of the Republic of Kazakhstan, Astana, Kazakhstan
First St. Petersburg State Medical University Named After I.I. acad. I.P. Pavlova, St. Petersburg, Russian Federation

Medical Center Hospital of the President’s Affairs Administration of the Republic of Kazakhstan
First St. Petersburg State Medical University Named After I.I. acad. I.P. Pavlova

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