Carbon nanoparticles neutralize carbon dioxide (CO2) in cytotoxicity: Potent carbon emission induced resistance to anticancer nanomedicine and antibiotics
Shaimoldina A. Sergazina A. Myrzagali S. Nazarbek G. Omarova Z. Mirza O. Fan H. Amin A. Zhou W. Xie Y.
15 March 2024Academic Press
Ecotoxicology and Environmental Safety
2024#273
Excessive carbon emissions, especially CO2 release, have been a global concern. Few studies applied nanotechnology to relieve the ecotoxicity of CO2. Here, we applied carbon dots (CDs) to neutralize the CO2. We found CO2 induced the aggregation of CDs, which is of significance for CDs in enhanced fluorescence intensity but decreased CDs function in nanozyme activity, and reduced CDs toxicity to bacteria and cancer cells. Our data suggest the concern of CO2 release in global health in CDs mediated anticancer drug delivery and antibiotics resistance. However, enhanced fluorescence in cells which can be applied for bioimaging or CO2 sensing as simulated investigation by static charged attraction of positively charged CDs with negatively charged soluble HCO3-. Thus, CO2 abrogates the nanomedicine efficacy in cancer cells and antibacterial and may induce drug resistance for patients undergoing chemotherapy or antibiotics therapy. To overcome the resistance, we may apply the CDs for a neutralization of CO2 for impact on anticancer nanomedicine and antibiotics and reducing the ecotoxicity in biological systems.
Cancer , Carbon dioxide , Carbon nanoparticles , Carbon neutralization , Nanomedicine
Text of the article Перейти на текст статьи
Department of Biology, School of Sciences and Humanities, Nazarbayev University, Astana, 010000, Kazakhstan
Department of Chemistry, School of Sciences and Humanities, Nazarbayev University, Astana, 010000, Kazakhstan
College of Medicine, Sharjah University, Sharjah, P. O. Box 27272, United Arab Emirates
College of Science, UAEU, Al Ain P. O. Box 15551, United Arab Emirates
School of Civil Engineering, Shandong University, Shandong, Jinan, 250000, China
Laboratory of water-sediment regulation and eco-decontamination, Shandong, Jinan, China
Department of Biology
Department of Chemistry
College of Medicine
College of Science
School of Civil Engineering
Laboratory of water-sediment regulation and eco-decontamination
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026