Iron-related Biomarkers in the Diagnosis and Management of Iron Disorders
Semenova Y. Bjørklund G. Butnariu M. Peana M.
2024Bentham Science Publishers
Current Medicinal Chemistry
2024#31Issue 274233 - 4248 pp.
Background: Iron deficiency and iron-related disorders are common health issues worldwide, affecting a significant proportion of the population. Diagnosis and management of these disorders rely heavily on using various iron-related biomarkers that can provide valuable clinical information. Objective: This review article provides an overview of the most commonly used iron-related biomarkers, including serum ferritin, transferrin saturation, soluble transferrin receptor, zinc protoporphyrin, and free erythrocyte protoporphyrin. Other emerging biomarkers, such as hepcidin and retinol-binding protein 4, are also discussed. Results: Iron plays a vital role in various physiological processes, including oxygen transport, energy metabolism, and DNA synthesis. The article highlights the advantages and limitations of iron biomarkers and their clinical applications in diagnosing and managing iron deficiency and iron-related anemia. Conclusion: Using iron-related biomarkers in screening and monitoring programs can improve patient outcomes and reduce healthcare costs.
biomarkers , hepcidin , Iron , iron deficiency , iron-related disorders , serum ferritin
Text of the article Перейти на текст статьи
Department of Research, Nazarbayev University School of Medicine, Astana, Kazakhstan
Department of Research, Council for Nutritional and Environmental Medicine, Mo i Rana, Norway
Department of Research, University of Life Sciences “King Mihai I” from Timisoara, Timis, Romania
CONEM Romania Biotechnology and Environmental Sciences Group, University of Life Sciences “King Mihai I” from Timisoara, Timis, Romania
Department of Chemical, Physical, Mathematical and Natural Sciences, University of Sassari, Sassari, Italy
Department of Research
Department of Research
Department of Research
CONEM Romania Biotechnology and Environmental Sciences Group
Department of Chemical
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026