Epidemiology of stroke and transient ischemic attacks in the population of the territories adjacent to the former Semipalatinsk Nuclear Test Site, Kazakhstan
Semenova Y. Rakhimova I. Nurpeissov T. Alikeyeva G. Khaibullin T. Kovalchuk V. Ainabekova Y. Yurkovskaya O. Glushkova N. Pivina L. Sarria-Santamera A. Abdrakhmanova Z. Abdrakhmanov A.
March 2022Springer Science and Business Media Deutschland GmbH
Radiation and Environmental Biophysics
2022#61Issue 117 - 28 pp.
The issue of radiation exposure as a potential cause of cerebrovascular disease raises many concerns. The aim of the present study was to investigate the epidemiology of stroke and transient ischemic attacks (TIA) along with the associated risk factors among the population of East Kazakhstan exposed to ionising radiation from the former Semipalatinsk Nuclear Test Site (SNTS) in comparison with the unexposed population of the same region. This 5-year retrospective cross-sectional study included the data on 10,970 patients, of whom the majority (62.3%) suffered from ischemic stroke, 11.7% had hemorrhagic stroke and the remaining 26.0% had TIA. At the moment when stroke/TIA happened, exposed patients were younger than the unexposed (mean age 63 years versus 64 years, p < 0.001) and showed higher rates of nearly all associated comorbidities, which commonly were more severe. Besides, exposed patients showed a higher risk of stroke lethality in contrast with the unexposed. The observed features might indicate that people residing in the vicinity of the SNTS are vulnerable to cerebrovascular disease and thus, this study contributes to timely recognition of this public health problem. In addition, a longitudinal study has to be envisaged to clarify whether there is any cause-effect relationship between exposure to radiation from the SNTS and the development of stroke or transient ischemic attacks.
Kazakhstan , Mortality , Radiation , Semipalatinsk Nuclear Test Site , Stroke , Transient ischemic attack
Text of the article Перейти на текст статьи
Department of Neurology, Ophthalmology and Otolaryngology, Semey Medical University, Semey, Kazakhstan
Department of Cardiology and Interventional Arrhythmology, Semey Medical University, Semey, Kazakhstan
Republican Center of Allergology, Almaty, Kazakhstan
Department of Public Health, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
Hospital No 38 named after N.I. Semashko, Saint Petersburg, Russian Federation
East Kazakhstan Regional Hospital, Stroke Center, Ust’-Kamenogorsk, Kazakhstan
Department of Personalized Medicine, Semey Medical University, Semey, Kazakhstan
Faculty of Medicine and Healthcare, Al-Farabi Kazakh National University, Almaty, Kazakhstan
Department of Emergency Medicine, Semey Medical University, Semey, Kazakhstan
School of Medicine, Nazarbayev University, Nur-Sultan, Kazakhstan
Department of Radiology and Nuclear Medicine, Astana Medical University, Nur-Sultan, Kazakhstan
Department of Interventional Arrhythmology, National Research Cardiac Surgery Center, Nur-Sultan, Kazakhstan
Department of Neurology
Department of Cardiology and Interventional Arrhythmology
Republican Center of Allergology
Department of Public Health
Hospital No 38 named after N.I. Semashko
East Kazakhstan Regional Hospital
Department of Personalized Medicine
Faculty of Medicine and Healthcare
Department of Emergency Medicine
School of Medicine
Department of Radiology and Nuclear Medicine
Department of Interventional Arrhythmology
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026