Kidney Transplantation in Kazakhstan: 10-Year Single Center Experience
Saparbay J. Assykbayev M. Abdugafarov S. Zhakhina G. Abisheva Z. Kuttymuratov G.
June 2021Elsevier Inc.
Transplantation Reports
2021#6Issue 2
Background: Kidney transplantation is considered the best available treatment option for patients with end-stage renal disease (ESRD).In the last decade, organ transplantation has been actively developing in Kazakhstan. Several transplant centers have been opened in 3 regions of Kazakhstan. Here we present the first report of 10-year experience of kidney transplantation in our center. Methods: Clinical data of the 416 cases of LDKT and DDKT from 2010 to 2020 were collected from electronic records. All data were retrospectively analyzed. Results: Among 416 kidney transplantations, 56 DDKT and 360 LDKT have been performed in our center from 2010 to 2020. The mean age of the recipient was 37.±12.5; 35.8 % female; 53.7% male. Chronic glomerulonephritis was the most common cause of renal failure in recipients (319 cases; 77%). The overall patient survival rates for 1, 3,5 years were 98.31 %; 97.97 %; 97.52 % respectively for kidney transplantation from a living donor and 98.18 % for all years from a deceased donor. The 1, 3, 5 and 7-year graft survival was 96.26%, 89.47%, 86.58% and 51.95% for the group from a deceased donor, while for the living donor group it was 97.46%, 96.84%, 95.96% and 92.85% respectively. Conclusions: Our clinical outcomes were comparable to other transplant centers in Kazakhstan. However, the proportion of deceased donor kidney transplants and highly sensitized recipients is very low. We believe that with a highly qualified multidimensional transplant team and improved protocols of donor and recipient selection, our center can improve our results and diminish the complications after transplantation.
Chronic kidney disease , Dialysis , ESRD , Kidney transplantation , Living donor
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Department of hepatology, gastroenterology and organ transplantation, LLP «National Research Oncology Center», Kerey and Zhanibek khandar street 3, Nur-Sultan, 01-0000, Kazakhstan
Department of science and education, LLP «National Research Oncology Center», Kerey and Zhanibek khandar street 3, Nur-Sultan, 01-0000, Kazakhstan
Department of nephrology, LLP «National Research Oncology Center», Kerey and Zhanibek khandar street 3, Nur-Sultan, 01-0000, Kazakhstan
Department of hepatology
Department of science and education
Department of nephrology
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