Probiotics and Fecal Transplant: An Intervention in Delaying Chronic Kidney Disease Progression?
Sanekommu H. Taj S. Mah Noor R. Umair Akmal M. Akhtar R. Hossain M. Asif A.
August 2023Multidisciplinary Digital Publishing Institute (MDPI)
Clinics and Practice
2023#13Issue 4881 - 888 pp.
Chronic kidney disease (CKD) is a global health challenge affecting nearly 700 million people worldwide. In the United States alone, the Medicare costs for CKD management has reached nearly USD 80 billion per year. While reversing CKD may be possible in the future, current strategies aim to slow its progression. For the most part, current management strategies have focused on employing Renin Angiotensin Aldosterone (RAS) inhibitors and optimizing blood pressure and diabetes mellitus control. Emerging data are showing that a disruption of the gut–kidney axis has a significant impact on delaying CKD progression. Recent investigations have documented promising results in using microbiota-based interventions to better manage CKD. This review will summarize the current evidence and explore future possibilities on the use of probiotics, prebiotics, synbiotics, and fecal microbial transplant to reduce CKD progression.
chronic kidney diseases , fecal microbiota transplantations , prebiotics , probiotics
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Department of Medicine, Jersey Shore University Medical Center, 1945 NJ-33, Neptune City, 07753, NJ, United States
School of Medicine, International University of Kyrgyzstan-International, Eastern Campus, Bishkek, 720007, Kyrgyzstan
Kazakh National Medical University, Almaty, 050012, Kazakhstan
Department of Gastroenterology, Jersey Shore University Medical Center, 1945 NJ-33, Neptune City, 07753, NJ, United States
Department of Medicine
School of Medicine
Kazakh National Medical University
Department of Gastroenterology
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