Optical Fiber Distributed Sensing Network for Thermal Mapping in Radiofrequency Ablation Neighboring a Blood Vessel
Sametova A. Kurmashev S. Ashikbayeva Z. Blanc W. Tosi D.
December 2022MDPI
Biosensors
2022#12Issue 12
Radiofrequency ablation (RFA) is a minimally invasive form of thermotherapy with great potential in cancer care, having the capability of selectively ablating tumoral masses with a surface area of several cm2. When performing RFA in the proximity of a blood vessel, the heating profile changes due to heat dissipation, perfusion, and impedance changes. In this work, we provide an experimental framework for the real-time evaluation of 2D thermal maps in RFA neighboring a blood vessel; the experimental setup is based on simultaneous scanning of multiple fibers in a distributed sensing network, achieving a spatial resolution of 2.5 × 4 mm2 in situ. We also demonstrate an increase of ablating potential when injecting an agarose gel in the tissue. Experimental results show that the heat-sink effect contributes to a reduction of the ablated region around 30–60% on average; however, the use of agarose significantly mitigates this effect, enlarging the ablated area by a significant amount, and ablating an even larger surface (+15%) in the absence of blood vessels.
cancer thermotherapies , distributed sensors , mini-invasive therapy , optical fiber sensors , radiofrequency ablation
Text of the article Перейти на текст статьи
School of Engineering and Digital Sciences, Nazarbayev University, Astana, 010000, Kazakhstan
National Laboratory Astana, Laboratory of Biosensors and Bioinstruments, Astana, 010000, Kazakhstan
Institute de Physique de Nice, CNRS UMR7010, Université Côte d’Azur, Avenue Joseph Vallot, Nice, 06108, France
School of Engineering and Digital Sciences
National Laboratory Astana
Institute de Physique de Nice
10 лет помогаем публиковать статьи Международный издатель
Книга Публикация научной статьи Волощук 2026 Book Publication of a scientific article 2026